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10.1302/2633-1462.68.BJO-2025-0067 http://scihub22266oqcxt.onion/10.1302/2633-1462.68.BJO-2025-0067 40784669!12335900!40784669     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=40784669&cmd=llinks): Failed to open stream: HTTP request failed! 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Impact of prior osteotomy and osteosynthesis on long-term outcomes after total hip arthroplasty : a 1:1 Mahalanobis distance-matched registry study of 5,392 patients |pdf=|usr=}}{{40784669}} gab.com Text Impact of prior osteotomy and osteosynthesis on long-term outcomes after total hip arthroplasty : a 1:1 Mahalanobis distance-matched registry study of 5,392 patients JO: Bone Jt Open http://www.kidney.de/pget.php?&tw=1&pmid=40784669 #FOAvip AIMS: Patients with a history of osteotomy or osteosynthesis pose distinct challenges in total hip arthroplasty (THA) due to altered anatomy and biomechanics. Although THA is an established intervention for degenerative hip disease, limited evidence exists on its long-term outcomes in this cohort, especially regarding revision rates, mortality, and complications. This registry study aimed to determine these outcomes using data from a large national registry. METHODS: This registry study analyzed data from the German Arthroplasty Registry (EPRD), which captures approximately 70% of all hip arthroplasties in Germany. Among 418,409 patients undergoing THA between November 2012 and March 2024, 5,392 were included after 1:1 Mahalanobis distance matching for age, sex, BMI, and comorbidities: 2,696 patients with a history of osteotomy or osteosynthesis compared with 2,696 patients without. Kaplan-Meier survival curves estimated revision and mortality risks over an eight-year follow-up. RESULTS: Over eight years, patients with prior osteotomy or osteosynthesis had significantly higher revision (6.8%, n = 183/2,696 vs 3.9%, n = 105/2,696, p = 0.002) and mortality (25.2%, n = 679/2,696 vs 20.4%, n = 550/2,696, p < 0.001) rates than those without prior hip surgery. Infection (17%, n = 22/131 vs 16%, n = 15/94), periprosthetic fracture (14%, n = 18/131 vs 12%, n = 11/94), and dislocation (14%, n = 18/131 vs 8.5%, n=8/94) were leading causes of revision. For cementless femoral components, prior-surgery patients had an eight-year revision rate of 7.3%, n = 143/1,957 compared with 3.6%, n = 71/1,958 (p = 0.003) and a mortality rate of 17.3%, n = 339/1,957 compared with 10.9%, n = 213/1,958 (p < 0.001). For cemented femoral components, revision rates were 4.9%, n = 36/739, compared with 4.7%, n = 35/738 (p = 0.330), and mortality 46.3%, n = 342/739, compared with 43.0%, n = 317/738 (p < 0.001). At one year, the revision rate in the prior-surgery group was already elevated at 3.7% (95% CI 3.1 to 4.5; n = 100/2,696) compared with 2.6% (95% CI 2.0 to 3.3; n = 70/2,696) in controls, diverging further over time. CONCLUSION: Patients with prior osteotomy or osteosynthesis undergoing THA face higher long-term revision and mortality risks, particularly with cementless stem fixation. Infection, periprosthetic fracture, and dislocation are key causes of revision. Twit Text FOAVip Impact of prior osteotomy and osteosynthesis on long-term outcomes after total hip arthroplasty : a 1:1 Mahalanobis distance-matched registry study of 5,392 patients ????Bone Jt Open http://www.kidney.de/pget.php?&tw=1&pmid=40784669 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40784669 #FOAvip English Wikipedia <ref>{{Cite pmid|40784669}}</ref> Impact of prior osteotomy and osteosynthesis on long-term outcomes after total hip arthroplasty : a 1:1 Mahalanobis distance-matched registry study of 5,392 patients #MMPMID40784669 Wagener N; Wu Y; Grimberg A; Hipfl C; Hardt S Bone Jt Open 2025[Aug]; 6 (8): 915-923 PMID40784669show ga AIMS: Patients with a history of osteotomy or osteosynthesis pose distinct challenges in total hip arthroplasty (THA) due to altered anatomy and biomechanics. Although THA is an established intervention for degenerative hip disease, limited evidence exists on its long-term outcomes in this cohort, especially regarding revision rates, mortality, and complications. This registry study aimed to determine these outcomes using data from a large national registry. METHODS: This registry study analyzed data from the German Arthroplasty Registry (EPRD), which captures approximately 70% of all hip arthroplasties in Germany. Among 418,409 patients undergoing THA between November 2012 and March 2024, 5,392 were included after 1:1 Mahalanobis distance matching for age, sex, BMI, and comorbidities: 2,696 patients with a history of osteotomy or osteosynthesis compared with 2,696 patients without. Kaplan-Meier survival curves estimated revision and mortality risks over an eight-year follow-up. RESULTS: Over eight years, patients with prior osteotomy or osteosynthesis had significantly higher revision (6.8%, n = 183/2,696 vs 3.9%, n = 105/2,696, p = 0.002) and mortality (25.2%, n = 679/2,696 vs 20.4%, n = 550/2,696, p < 0.001) rates than those without prior hip surgery. Infection (17%, n = 22/131 vs 16%, n = 15/94), periprosthetic fracture (14%, n = 18/131 vs 12%, n = 11/94), and dislocation (14%, n = 18/131 vs 8.5%, n=8/94) were leading causes of revision. For cementless femoral components, prior-surgery patients had an eight-year revision rate of 7.3%, n = 143/1,957 compared with 3.6%, n = 71/1,958 (p = 0.003) and a mortality rate of 17.3%, n = 339/1,957 compared with 10.9%, n = 213/1,958 (p < 0.001). For cemented femoral components, revision rates were 4.9%, n = 36/739, compared with 4.7%, n = 35/738 (p = 0.330), and mortality 46.3%, n = 342/739, compared with 43.0%, n = 317/738 (p < 0.001). At one year, the revision rate in the prior-surgery group was already elevated at 3.7% (95% CI 3.1 to 4.5; n = 100/2,696) compared with 2.6% (95% CI 2.0 to 3.3; n = 70/2,696) in controls, diverging further over time. CONCLUSION: Patients with prior osteotomy or osteosynthesis undergoing THA face higher long-term revision and mortality risks, particularly with cementless stem fixation. Infection, periprosthetic fracture, and dislocation are key causes of revision. äImpact of prior osteotomy and osteosynthesis on long-term outcomes aft(epmc).pdf DeepDyve Pubget Overpricing