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10.1177/23247096251352371 http://scihub22266oqcxt.onion/10.1177/23247096251352371 40642834!ä!40642834 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=40642834&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40642834.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Investig+Med+High+Impact+Case+Rep 2025 ; 13 (ä): 23247096251352371 Nephropedia Template TP {{tp|p=40642834|t=2025. High-Dose Insulin Euglycemic Therapy in Concomitant Beta-Blocker and Calcium Channel Blocker Overdose |pdf=|usr=}}{{40642834}} gab.com Text High-Dose Insulin Euglycemic Therapy in Concomitant Beta-Blocker and Calcium Channel Blocker Overdose JO: J Investig Med High Impact Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=40642834 #FOAvip Beta-blockers and calcium channel blockers are among the most commonly used drugs in the adult population, and the National Poison Data System annual reports note 11 075 beta-blocker overdoses and 6256 calcium-channel blocker overdoses in 2022. Poisoning with these medications presents clinically with profound bradycardia, depression of myocyte contractility, and vasodilation resulting in hemodynamic instability often refractory to initial vasopressor treatment. Herein we present a case of concomitant beta-blocker and calcium-channel blocker overdose with hypotension refractory to vasopressors successfully managed with high-dose insulin euglycemic therapy. Close monitoring is required to prevent adverse effects from therapy, which are predictable: hypokalemia and hypoglycemia often result from the use of up to hundreds of units of insulin per hour, as was done in this case. Frequent monitoring is required to safely utilize high-dose insulin euglycemic therapy, which has a good safety profile when appropriate monitoring is utilized. Twit Text FOAVip High-Dose Insulin Euglycemic Therapy in Concomitant Beta-Blocker and Calcium Channel Blocker Overdose ????J Investig Med High Impact Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=40642834 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40642834 #FOAvip English Wikipedia <ref>{{Cite pmid|40642834}}</ref> High-Dose Insulin Euglycemic Therapy in Concomitant Beta-Blocker and Calcium Channel Blocker Overdose #MMPMID40642834 Roperia V; Kiani AZ; Jayakumar N J Investig Med High Impact Case Rep 2025[Jan]; 13 (ä): 23247096251352371 PMID40642834show ga Beta-blockers and calcium channel blockers are among the most commonly used drugs in the adult population, and the National Poison Data System annual reports note 11 075 beta-blocker overdoses and 6256 calcium-channel blocker overdoses in 2022. Poisoning with these medications presents clinically with profound bradycardia, depression of myocyte contractility, and vasodilation resulting in hemodynamic instability often refractory to initial vasopressor treatment. Herein we present a case of concomitant beta-blocker and calcium-channel blocker overdose with hypotension refractory to vasopressors successfully managed with high-dose insulin euglycemic therapy. Close monitoring is required to prevent adverse effects from therapy, which are predictable: hypokalemia and hypoglycemia often result from the use of up to hundreds of units of insulin per hour, as was done in this case. Frequent monitoring is required to safely utilize high-dose insulin euglycemic therapy, which has a good safety profile when appropriate monitoring is utilized. |*Adrenergic beta-Antagonists/poisoning[MESH] |*Calcium Channel Blockers/poisoning[MESH] |*Drug Overdose/drug therapy[MESH] |*Hypoglycemic Agents/administration & dosage[MESH] |*Hypotension/chemically induced/drug therapy[MESH] |*Insulin/administration & dosage/therapeutic use[MESH] |Adult[MESH] |Female[MESH] |Humans[MESH] |Male[MESH]High-Dose Insulin Euglycemic Therapy in Concomitant Beta-Blocker and C(epmc).pdf DeepDyve Pubget Overpricing