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10.1186/s12890-025-03773-z http://scihub22266oqcxt.onion/10.1186/s12890-025-03773-z 40611169!ä!40611169 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40611169.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMC+Pulm+Med 2025 ; 25 (1): 308 Nephropedia Template TP {{tp|p=40611169|t=2025. Factors associated with the intubation of patients with acute respiratory failure and their impact on mortality: a retrospective cohort study |pdf=|usr=}}{{40611169}} gab.com Text Factors associated with the intubation of patients with acute respiratory failure and their impact on mortality: a retrospective cohort study JO: BMC Pulm Med http://www.kidney.de/pget.php?&tw=1&pmid=40611169 #FOAvip BACKGROUND: Severe respiratory failure often requires invasive mechanical ventilation, identifying the factors that lead to this need is crucial. This study aims to identify risk factors for invasive mechanical ventilation and clinical outcomes in patients with acute respiratory failure from the time of onset of symptoms to respiratory failure. METHODS: This retrospective cohort included adults with confirmed COVID-19 admitted to Intermediate or Intensive Care Units between May 1, 2020, and May 1, 2021. Inclusion required chest computed tomography (CT) and inflammatory markers (CRP, D-dimer, ferritin, IL-6) within 72 h of admission. The primary outcome was the need for orotracheal intubation and its association with mortality. Multivariate Cox regression and time-stratified analyses were performed. RESULTS: Of 550 patients, 346 (63%) required intubation. The overall in-hospital mortality rate was 21.6%. Intubated patients had higher BMI (p = 0.02), SAPS-3 scores (p < 0.001), and elevated CRP, IL-6, and D-dimer. CT findings showed greater lung consolidation, especially after the second week. SAPS 3 and time from symptom onset to intubation were independent predictors of mortality. Patients intubated >/= 15 days after symptom onset had significantly higher mortality (OR = 2.13; 95% CI: 1.07-4.23), despite similar oxygenation levels at the time of intubation. These patients also had longer use of non-invasive support. CONCLUSION: Delayed intubation beyond 15 days from symptom onset is associated with increased mortality. Integrating inflammatory markers and CT findings may help identify patients at risk for clinical deterioration. Timely transition from non-invasive to invasive support may improve outcomes. Twit Text FOAVip Factors associated with the intubation of patients with acute respiratory failure and their impact on mortality: a retrospective cohort study ????BMC Pulm Med http://www.kidney.de/pget.php?&tw=1&pmid=40611169 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40611169 #FOAvip English Wikipedia <ref>{{Cite pmid|40611169}}</ref> Factors associated with the intubation of patients with acute respiratory failure and their impact on mortality: a retrospective cohort study #MMPMID40611169 Hohmann FB; Midega TD; Treml RE; Galindo VB; Veiga G; Machado I; Kraft MR; Custodio S; Paolinelli E; Galdino F; Silva JM Jr BMC Pulm Med 2025[Jul]; 25 (1): 308 PMID40611169show ga BACKGROUND: Severe respiratory failure often requires invasive mechanical ventilation, identifying the factors that lead to this need is crucial. This study aims to identify risk factors for invasive mechanical ventilation and clinical outcomes in patients with acute respiratory failure from the time of onset of symptoms to respiratory failure. METHODS: This retrospective cohort included adults with confirmed COVID-19 admitted to Intermediate or Intensive Care Units between May 1, 2020, and May 1, 2021. Inclusion required chest computed tomography (CT) and inflammatory markers (CRP, D-dimer, ferritin, IL-6) within 72 h of admission. The primary outcome was the need for orotracheal intubation and its association with mortality. Multivariate Cox regression and time-stratified analyses were performed. RESULTS: Of 550 patients, 346 (63%) required intubation. The overall in-hospital mortality rate was 21.6%. Intubated patients had higher BMI (p = 0.02), SAPS-3 scores (p < 0.001), and elevated CRP, IL-6, and D-dimer. CT findings showed greater lung consolidation, especially after the second week. SAPS 3 and time from symptom onset to intubation were independent predictors of mortality. Patients intubated >/= 15 days after symptom onset had significantly higher mortality (OR = 2.13; 95% CI: 1.07-4.23), despite similar oxygenation levels at the time of intubation. These patients also had longer use of non-invasive support. CONCLUSION: Delayed intubation beyond 15 days from symptom onset is associated with increased mortality. Integrating inflammatory markers and CT findings may help identify patients at risk for clinical deterioration. Timely transition from non-invasive to invasive support may improve outcomes. |*COVID-19/mortality/complications/therapy[MESH] |*Intubation, Intratracheal/statistics & numerical data[MESH] |*Respiration, Artificial/statistics & numerical data[MESH] |*Respiratory Insufficiency/therapy/mortality/etiology[MESH] |Aged[MESH] |C-Reactive Protein[MESH] |Female[MESH] |Fibrin Fibrinogen Degradation Products[MESH] |Hospital Mortality[MESH] |Humans[MESH] |Interleukin-6/blood[MESH] |Male[MESH] |Middle Aged[MESH] |Retrospective Studies[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH]Factors associated with the intubation of patients with acute respirat(epmc).pdf DeepDyve Pubget Overpricing