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10.1186/s12893-025-03028-y

http://scihub22266oqcxt.onion/10.1186/s12893-025-03028-y
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40611152!12226860!40611152
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suck abstract from ncbi


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pmid40611152      BMC+Surg 2025 ; 25 (1): 270
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  • Clinical application of preoperative volumetric measurement for interventional precise embolization in the treatment of hypersplenism caused by liver cirrhosis #MMPMID40611152
  • Hu YB; Duan L; Liu GY; Wang XM
  • BMC Surg 2025[Jul]; 25 (1): 270 PMID40611152show ga
  • OBJECTIVE: Volume measurement software is not routinely utilized in clinical practice before splenic artery embolization. To explore the function of such software measurement in this context, we conducted a retrospective study. METHODS: We divided patients into two groups: 38 patients in Group A underwent three-dimensional reconstruction using Revolution CT, and 37 patients in Group B underwent imaging with normal CT technology. We compared the changes in liver function test results and haematological parameters between these two groups. RESULTS: A total of 75 patients who underwent splenic artery embolization from January 2018 to January 2023 were included. The preoperative baseline data were not significantly different (all P values > 0.05). Both groups showed improvements in liver function and hypersplenism-related parameters. Within 2 weeks after surgery, Group A had significantly greater WBC (5.54 +/- 1.92 x 10;9/L) and PLT (65.80 +/- 20.12 x 10;9/L) counts than Group B (WBC: 4.14 +/- 1.96 x 10;9/L; PLT: 52.70 +/- 14.78 x 10;9/L; P < 0.05), indicating better control of hypersplenism. At 2 months postintervention, Group A demonstrated more favourable improvements in postintervention splenic volume (reduced from 1045 +/- 122.9 cm(3) to 489.5 +/- 84.93 cm(3)), portal vein diameter (from 1.51 +/- 0.19 cm to 1.28 +/- 0.13 cm), and portal vein flow velocity (increased from 17.70 +/- 5.25 cm/s to 23.56 +/- 6.40 cm/s) than Group B. Moreover, a 53.2% splenic volume reduction was noted in Group A, which was significantly greater than the 31.4% reduction in Group B. Additionally, Group A had fewer adverse reactions, with lower liver/gastrointestinal toxicity (chi(2)=4.242, P = 0.039) and fever severity (chi(2)= 4.805, P = 0.028). CONCLUSIONS: This study suggests that using Revolution CT prior to splenic artery embolization provides an effective method for managing hypersplenism, enhancing liver function, and reducing the risk of complications.
  • |*Embolization, Therapeutic/methods[MESH]
  • |*Hypersplenism/etiology/therapy/diagnostic imaging[MESH]
  • |*Liver Cirrhosis/complications[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Imaging, Three-Dimensional[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Preoperative Care/methods[MESH]
  • |Retrospective Studies[MESH]
  • |Splenic Artery[MESH]


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