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10.3348/kjr.2024.1261 http://scihub22266oqcxt.onion/10.3348/kjr.2024.1261 40590075!ä!40590075 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40590075.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Korean+J+Radiol 2025 ; 26 (7): 626-637 Nephropedia Template TP {{tp|p=40590075|t=2025. Impact of Aortic Stenosis Severity on Left Heart Function Analyzed Using CT-Derived Strain Parameters |pdf=|usr=}}{{40590075}} gab.com Text Impact of Aortic Stenosis Severity on Left Heart Function Analyzed Using CT-Derived Strain Parameters JO: Korean J Radiol http://www.kidney.de/pget.php?&tw=1&pmid=40590075 #FOAvip OBJECTIVE: This study aimed to evaluate changes in left ventricular and left atrial mechanics in relation to the severity of aortic stenosis (AS) by comparing computed tomography (CT)-derived strain values in patients with mild-to-severe AS. MATERIALS AND METHODS: This single-center retrospective study included 120 patients (median age, 76 years; 45.0% male), comprising 30, 30, and 60 patients with mild, moderate, and severe AS, respectively, all of whom underwent multiphase cardiac CT between 2015 and 2021. Patients were selected from 177 individuals who met the initial eligibility criteria, with matching for age, sex, and hypertension in a 1:1:2 ratio across the mild, moderate, and severe AS groups. Electrocardiography-gated cardiac CT images were analyzed to obtain various quantitative left ventricle (LV) and left atrium (LA) strain parameters. Statistical differences in cardiac CT-derived LV and LA strain parameters among mild, moderate, and severe AS were evaluated using the Kruskal-Wallis test, followed by post-hoc tests. RESULTS: The median LV global longitudinal strain differed significantly across AS severity (GLS: -19.4%, -18.2%, and -16.2% for mild, moderate, and severe AS, respectively; P < 0.001), with the absolute value decreasing as AS severity increased. Additionally, the median values of LV global circumferential strain (GCS: -29.8%, -30.8%, and -27.4%, respectively; P = 0.045), LV global radial strain (GRS: 50.1%, 50.3%, and 39.3%, respectively; P = 0.004), and LA conduit strain (11.5%, 11.2%, and 9.0%, respectively; P = 0.031) differed significantly according to AS severity, with lower absolute values observed in patients with severe AS. CONCLUSION: In patients with AS, CT-derived LV and LA strains revealed changes in myocardial deformation according to AS severity. Specifically, there was a gradual decrease in the absolute value of LV GLS with increasing AS severity and initial preservation until moderate AS, followed by an eventual decrease in the absolute values of LV GCS, LV GRS, and LA conduit strain in severe AS. Twit Text FOAVip Impact of Aortic Stenosis Severity on Left Heart Function Analyzed Using CT-Derived Strain Parameters ????Korean J Radiol http://www.kidney.de/pget.php?&tw=1&pmid=40590075 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40590075 #FOAvip English Wikipedia <ref>{{Cite pmid|40590075}}</ref> Impact of Aortic Stenosis Severity on Left Heart Function Analyzed Using CT-Derived Strain Parameters #MMPMID40590075 Park S; Lee SA; Lee JE; Kang JW; Yang DH; Koo HJ Korean J Radiol 2025[Jul]; 26 (7): 626-637 PMID40590075show ga OBJECTIVE: This study aimed to evaluate changes in left ventricular and left atrial mechanics in relation to the severity of aortic stenosis (AS) by comparing computed tomography (CT)-derived strain values in patients with mild-to-severe AS. MATERIALS AND METHODS: This single-center retrospective study included 120 patients (median age, 76 years; 45.0% male), comprising 30, 30, and 60 patients with mild, moderate, and severe AS, respectively, all of whom underwent multiphase cardiac CT between 2015 and 2021. Patients were selected from 177 individuals who met the initial eligibility criteria, with matching for age, sex, and hypertension in a 1:1:2 ratio across the mild, moderate, and severe AS groups. Electrocardiography-gated cardiac CT images were analyzed to obtain various quantitative left ventricle (LV) and left atrium (LA) strain parameters. Statistical differences in cardiac CT-derived LV and LA strain parameters among mild, moderate, and severe AS were evaluated using the Kruskal-Wallis test, followed by post-hoc tests. RESULTS: The median LV global longitudinal strain differed significantly across AS severity (GLS: -19.4%, -18.2%, and -16.2% for mild, moderate, and severe AS, respectively; P < 0.001), with the absolute value decreasing as AS severity increased. Additionally, the median values of LV global circumferential strain (GCS: -29.8%, -30.8%, and -27.4%, respectively; P = 0.045), LV global radial strain (GRS: 50.1%, 50.3%, and 39.3%, respectively; P = 0.004), and LA conduit strain (11.5%, 11.2%, and 9.0%, respectively; P = 0.031) differed significantly according to AS severity, with lower absolute values observed in patients with severe AS. CONCLUSION: In patients with AS, CT-derived LV and LA strains revealed changes in myocardial deformation according to AS severity. Specifically, there was a gradual decrease in the absolute value of LV GLS with increasing AS severity and initial preservation until moderate AS, followed by an eventual decrease in the absolute values of LV GCS, LV GRS, and LA conduit strain in severe AS. |*Aortic Valve Stenosis/diagnostic imaging/physiopathology[MESH] |*Tomography, X-Ray Computed/methods[MESH] |*Ventricular Function, Left[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Female[MESH] |Heart Atria/diagnostic imaging/physiopathology[MESH] |Heart Ventricles/diagnostic imaging/physiopathology[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Retrospective Studies[MESH]Impact of Aortic Stenosis Severity on Left Heart Function Analyzed Usi(epmc).pdf DeepDyve Pubget Overpricing