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10.4103/jisppd.jisppd_146_25 http://scihub22266oqcxt.onion/10.4103/jisppd.jisppd_146_25 40586464!ä!40586464 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40586464.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Indian+Soc+Pedod+Prev+Dent 2025 ; 43 (2): 231-235 Nephropedia Template TP {{tp|p=40586464|t=2025. Effect of Lactobacillus reuteri probiotic on gingival index and Interleukin-1beta levels of children with thalassemia experiencing gingivitis |pdf=|usr=}}{{40586464}} gab.com Text Effect of Lactobacillus reuteri probiotic on gingival index and Interleukin-1beta levels of children with thalassemia experiencing gingivitis JO: J Indian Soc Pedod Prev Dent http://www.kidney.de/pget.php?&tw=1&pmid=40586464 #FOAvip CONTEXT: Thalassemia is a genetic blood disorder caused by gene mutation leading to chronic anemia, and patients will need routine blood transfusions as a lifetime supportive therapy. Previous studies show high prevalence of periodontal disease in patients who receive routine blood transfusions. Recent studies found probiotic supplementation as an adjuvant therapy in managing periodontal disease. AIMS: This study aimed to analyze the effect of Lactobacillus reuteri probiotic consumption on gingival index and salivary interleukin-1beta levels of children with thalassemia experiencing gingivitis. SETTINGS AND DESIGN: This was an evaluative study conducted at a tertiary care hospital in Jakarta, Indonesia. PARTICIPANTS AND METHODS: In this study, 16 children aged 6-12 with thalassemia major were recruited in Instalasi Pelayanan Terpadu Kesehatan Ibu dan Anak RSUPN Dr. Cipto Mangunkusumo. Dental health education and Lactobacillus L. reuteri probiotics supplementation 1x/day for 14 days were given to all participants. The gingival index by Lobene was measured at baseline and day 14. Salivary interleukin-1beta levels were tested by ELISA Kit in a laboratory. STATISTICAL ANALYSIS USED: Dependent t-test. RESULTS: There was a significant difference in gingival index and salivary interleukin-1beta levels of children with thalassemia after consuming L. reuteri probiotics for 14 days. CONCLUSION: L. reuteri probiotic consumption for 14 days significantly reduced the gingival index and salivary interleukin-1beta levels of children with thalassemia experiencing gingivitis. Twit Text FOAVip Effect of Lactobacillus reuteri probiotic on gingival index and Interleukin-1beta levels of children with thalassemia experiencing gingivitis ????J Indian Soc Pedod Prev Dent http://www.kidney.de/pget.php?&tw=1&pmid=40586464 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40586464 #FOAvip English Wikipedia <ref>{{Cite pmid|40586464}}</ref> Effect of Lactobacillus reuteri probiotic on gingival index and Interleukin-1beta levels of children with thalassemia experiencing gingivitis #MMPMID40586464 Sumendap IB; Sutadi H; Fauziah E; Wahidiyat PA J Indian Soc Pedod Prev Dent 2025[Apr]; 43 (2): 231-235 PMID40586464show ga CONTEXT: Thalassemia is a genetic blood disorder caused by gene mutation leading to chronic anemia, and patients will need routine blood transfusions as a lifetime supportive therapy. Previous studies show high prevalence of periodontal disease in patients who receive routine blood transfusions. Recent studies found probiotic supplementation as an adjuvant therapy in managing periodontal disease. AIMS: This study aimed to analyze the effect of Lactobacillus reuteri probiotic consumption on gingival index and salivary interleukin-1beta levels of children with thalassemia experiencing gingivitis. SETTINGS AND DESIGN: This was an evaluative study conducted at a tertiary care hospital in Jakarta, Indonesia. PARTICIPANTS AND METHODS: In this study, 16 children aged 6-12 with thalassemia major were recruited in Instalasi Pelayanan Terpadu Kesehatan Ibu dan Anak RSUPN Dr. Cipto Mangunkusumo. Dental health education and Lactobacillus L. reuteri probiotics supplementation 1x/day for 14 days were given to all participants. The gingival index by Lobene was measured at baseline and day 14. Salivary interleukin-1beta levels were tested by ELISA Kit in a laboratory. STATISTICAL ANALYSIS USED: Dependent t-test. RESULTS: There was a significant difference in gingival index and salivary interleukin-1beta levels of children with thalassemia after consuming L. reuteri probiotics for 14 days. CONCLUSION: L. reuteri probiotic consumption for 14 days significantly reduced the gingival index and salivary interleukin-1beta levels of children with thalassemia experiencing gingivitis. |*Gingivitis/therapy/etiology[MESH] |*Interleukin-1beta/metabolism/analysis[MESH] |*Limosilactobacillus reuteri[MESH] |*Periodontal Index[MESH] |*Probiotics/therapeutic use[MESH] |*Thalassemia/complications[MESH] |Child[MESH] |Female[MESH] |Humans[MESH] |Male[MESH]Effect of Lactobacillus reuteri probiotic on gingival index and Interl(epmc).pdf DeepDyve Pubget Overpricing