Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.5603/ep.104464 http://scihub22266oqcxt.onion/10.5603/ep.104464 40586406!ä!40586406 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=40586406&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40586406.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Endokrynol+Pol 2025 ; 76 (3): 301-312 Nephropedia Template TP {{tp|p=40586406|t=2025. Association between the cumulative metabolic score for insulin resistance and diabetes mellitus incidence: a prospective nationwide cohort study in China |pdf=|usr=}}{{40586406}} gab.com Text Association between the cumulative metabolic score for insulin resistance and diabetes mellitus incidence: a prospective nationwide cohort study in China JO: Endokrynol Pol http://www.kidney.de/pget.php?&tw=1&pmid=40586406 #FOAvip INTRODUCTION: The relationship between changes in metabolic score for insulin resistance (METS-IR) and diabetes mellitus (DM) remains to be elucidated. The present study sought to explore whether changes in METS-IR were associated with incident DM. MATERIAL AND METHODS: This study included 4031 individuals aged over 45 years from the China Health and Retirement Longitudinal Study. Utilizing the K-Means clustering method, participants were divided into four groups. Cumulative METS-IR was employed as a quantitative indicator reflecting changes in METS-IR. Multivariable logistic regression models and restricted cubic splines (RCS) were employed to assess the relationship between changes in METS-IR and DM. RESULTS: During the five-year follow-up, 338 (8.4%) incident DM cases were identified. After adjusting for potential confounders, compared to class 1, the incident DM was significantly higher in class 4 [odds ratio (OR): 2.731, 95% confidence interval (CI): 1.411-5.527, p = 0.003]. When cumulative METS-IR (per SD increase) was introduced as a continuous variable into the multivariate regression model, the association remained significant in Model 3 (OR: 1.393, 95% CI: 1.125-1.715, p = 0.003). Additionally, when cumulative METS-IR was categorized into quartiles, compared to the first quartile, the incident DM was significantly higher in the fourth quartile (OR: 2.022, 95% CI: 1.171-3.501, p = 0.011). In addition, cumulative METS-IR exhibited a nonlinear association with DM (poverall = 0.001, pnon linear = 0.038). CONCLUSIONS: Substantial changes in METS-IR were independently associated with the risk of DM in middle-aged and elderly Chinese people. Long-term METS-IR monitoring is significant for early identification and prevention of DM, with significant implications for clinical practice. Twit Text FOAVip Association between the cumulative metabolic score for insulin resistance and diabetes mellitus incidence: a prospective nationwide cohort study in China ????Endokrynol Pol http://www.kidney.de/pget.php?&tw=1&pmid=40586406 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40586406 #FOAvip English Wikipedia <ref>{{Cite pmid|40586406}}</ref> Association between the cumulative metabolic score for insulin resistance and diabetes mellitus incidence: a prospective nationwide cohort study in China #MMPMID40586406 Wen S; Huang X; Huang Z; Deng Z; Zhou C; Chen N; Huang Y Endokrynol Pol 2025[]; 76 (3): 301-312 PMID40586406show ga INTRODUCTION: The relationship between changes in metabolic score for insulin resistance (METS-IR) and diabetes mellitus (DM) remains to be elucidated. The present study sought to explore whether changes in METS-IR were associated with incident DM. MATERIAL AND METHODS: This study included 4031 individuals aged over 45 years from the China Health and Retirement Longitudinal Study. Utilizing the K-Means clustering method, participants were divided into four groups. Cumulative METS-IR was employed as a quantitative indicator reflecting changes in METS-IR. Multivariable logistic regression models and restricted cubic splines (RCS) were employed to assess the relationship between changes in METS-IR and DM. RESULTS: During the five-year follow-up, 338 (8.4%) incident DM cases were identified. After adjusting for potential confounders, compared to class 1, the incident DM was significantly higher in class 4 [odds ratio (OR): 2.731, 95% confidence interval (CI): 1.411-5.527, p = 0.003]. When cumulative METS-IR (per SD increase) was introduced as a continuous variable into the multivariate regression model, the association remained significant in Model 3 (OR: 1.393, 95% CI: 1.125-1.715, p = 0.003). Additionally, when cumulative METS-IR was categorized into quartiles, compared to the first quartile, the incident DM was significantly higher in the fourth quartile (OR: 2.022, 95% CI: 1.171-3.501, p = 0.011). In addition, cumulative METS-IR exhibited a nonlinear association with DM (poverall = 0.001, pnon linear = 0.038). CONCLUSIONS: Substantial changes in METS-IR were independently associated with the risk of DM in middle-aged and elderly Chinese people. Long-term METS-IR monitoring is significant for early identification and prevention of DM, with significant implications for clinical practice. |*Diabetes Mellitus/epidemiology/metabolism[MESH] |*Insulin Resistance[MESH] |Aged[MESH] |China/epidemiology[MESH] |Female[MESH] |Humans[MESH] |Incidence[MESH] |Longitudinal Studies[MESH] |Male[MESH] |Middle Aged[MESH] |Prospective Studies[MESH]Association between the cumulative metabolic score for insulin resista(epmc).pdf DeepDyve Pubget Overpricing