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10.1080/08941939.2025.2523858

http://scihub22266oqcxt.onion/10.1080/08941939.2025.2523858
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40586267!ä!40586267

suck abstract from ncbi


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pmid40586267      J+Invest+Surg 2025 ; 38 (1): 2523858
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  • An Epidemiological Study on Survival in Lymphoma of Mucosa-Associated Lymphoid Tissue: A Comparative Analysis by Primary Tumor Location #MMPMID40586267
  • Chen GP; Lu ZZ; Lu GZ; Zhou Y; Wu SG
  • J Invest Surg 2025[Dec]; 38 (1): 2523858 PMID40586267show ga
  • PURPOSE: To investigate outcome and local treatment strategy for extranodal mucosa-associated lymphoid tissue (MALT) lymphoma patients. METHODS: Retrospectively collected patients using the data from the Surveillance, Epidemiology, and End Results database, including tumor sites with over 200 cases. RESULTS: The cohort comprised 3842 patients, with the gastric region being the most prevalent site (34.9%), followed by salivary gland (16.8%), cutaneous (16.5%), pulmonary (13.3%), intestinal (13.2%), and head and neck (5.4%). The 10-year cancer-specific survival (CSS) was 88.1%, 92.6%, 86.5%, 87.7%, 89.7%, and 97.7% in patients with tumors located in the gastric, salivary gland, pulmonary, head and neck, intestinal, and cutaneous, respectively (p < 0.001). Compared to gastric MALT lymphoma, the cutaneous site exhibited superior CSS (p < 0.001), whereas other sites showed comparable outcomes (all p >/= 0.05). In gastric MALT lymphoma cases, radiotherapy was associated with better CSS than surgery alone (p < 0.001), while no significant difference was observed between surgery plus radiotherapy versus surgery alone (p = 0.561). Treatment outcomes were similar across the three therapeutic modalities for non-gastric sites. CONCLUSIONS: Our findings underscore the biological and clinical heterogeneity of extranodal MALT lymphoma. While localized treatments provide equivalent results across most non-gastric sites, radiotherapy is recommended as the primary noninvasive treatment option.
  • |*Lymphoma, B-Cell, Marginal Zone/mortality/therapy/pathology/epidemiology[MESH]
  • |*Stomach Neoplasms/mortality/therapy/pathology[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Female[MESH]
  • |Head and Neck Neoplasms/mortality/therapy[MESH]
  • |Humans[MESH]
  • |Intestinal Neoplasms/mortality/therapy[MESH]
  • |Lung Neoplasms/mortality/therapy[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]
  • |SEER Program/statistics & numerical data[MESH]
  • |Salivary Gland Neoplasms/mortality/therapy[MESH]
  • |Skin Neoplasms/mortality/therapy[MESH]
  • |Treatment Outcome[MESH]
  • |United States/epidemiology[MESH]


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