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10.1007/BF02106133

http://scihub22266oqcxt.onion/10.1007/BF02106133
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4000904!ä!4000904

suck abstract from ncbi


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pmid4000904      Pharm+Weekbl+Sci 1985 ; 7 (2): 79-82
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  • Colorimetric analysis of some diuretic drugs: hydrochlorothiazide and spironolactone #MMPMID4000904
  • Moussa BA; el Kousy NM
  • Pharm Weekbl Sci 1985[Apr]; 7 (2): 79-82 PMID4000904show ga
  • Two convenient spectrophotometric methods were developed for the determination of hydrochlorothiazide and spironolactone. A specific colour reaction for the determination of hydrochlorothiazide is reported. One method is based on the reaction of hydrochlorothiazide with n-butylamine and cobaltous chloride in anhydrous methanol. A blue-violet colour is produced and is measured at 570 nm. A highly selective colorimetric method was adopted for the analysis of spironolactone by reacting with isoniazid forming a coloured hydrazone derivative and subsequent measurement of the coloured product at 405 nm.
  • |Chemical Phenomena[MESH]
  • |Chemistry[MESH]
  • |Cobalt[MESH]
  • |Colorimetry[MESH]
  • |Hydrochlorothiazide/*analysis[MESH]
  • |Hydrogen-Ion Concentration[MESH]
  • |Spironolactone/*analysis[MESH]
  • |Tablets[MESH]


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