Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1152/ajprenal.1985.249.3.F346 http://scihub22266oqcxt.onion/10.1152/ajprenal.1985.249.3.F346 3929622!ä!3929622 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Physiol 1985 ; 249 (3 Pt 2): F346-55 Nephropedia Template TP {{tp|p=3929622|t=1985. Effect of calcium on transport characteristics of cultured proximal renal cells |pdf=|usr=}}{{3929622}} gab.com Text Effect of calcium on transport characteristics of cultured proximal renal cells JO: Am J Physiol http://www.kidney.de/pget.php?&tw=1&pmid=3929622 #FOAvip We examined the effects of acute changes in extracellular and intracellular calcium on transport processes in primary culture of proximal rabbit renal cells. A change in extracellular calcium from 0 to 3 mM inhibited amiloride-sensitive sodium uptake by 30%, and this effect was maximal at 1 mM calcium. Other polyvalent cations (Mn2+, Mg2+, La3+, and Ba2+) produced quantitatively similar inhibition of amiloride-sensitive sodium uptake compared with calcium. An increase in cytosolic calcium produced by calcium loading (20 mM) or by A23187 (20 microM) resulted in an inhibition of 25-40% of amiloride-sensitive sodium uptake. Moreover, quinidine (10(-4)M) and ruthenium red (3 microM), agents presumed to increase cytosolic calcium, inhibited amiloride-sensitive sodium uptake by 20-60%. Both these agents also inhibited sodium-dependent phosphate uptake by 20% but had no effect on ouabain-sensitive 86Rb+ uptake or on sodium-dependent alpha-methylglucoside uptake. Our data indicate that increases in extracellular calcium inhibit amiloride-sensitive sodium uptake and increases in cytosolic calcium inhibit sodium-dependent phosphate and amiloride-sensitive sodium uptakes. The effect of extracellular calcium may be due to charge screening and/or binding to the negatively charged plasma membrane or due to alterations in membrane fluidity. Twit Text FOAVip Effect of calcium on transport characteristics of cultured proximal renal cells ????Am J Physiol http://www.kidney.de/pget.php?&tw=1&pmid=3929622 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=3929622 #FOAvip English Wikipedia <ref>{{Cite pmid|3929622}}</ref> Effect of calcium on transport characteristics of cultured proximal renal cells #MMPMID3929622 Sakhrani LM; Tessitore N; Massry SG Am J Physiol 1985[Sep]; 249 (3 Pt 2): F346-55 PMID3929622show ga We examined the effects of acute changes in extracellular and intracellular calcium on transport processes in primary culture of proximal rabbit renal cells. A change in extracellular calcium from 0 to 3 mM inhibited amiloride-sensitive sodium uptake by 30%, and this effect was maximal at 1 mM calcium. Other polyvalent cations (Mn2+, Mg2+, La3+, and Ba2+) produced quantitatively similar inhibition of amiloride-sensitive sodium uptake compared with calcium. An increase in cytosolic calcium produced by calcium loading (20 mM) or by A23187 (20 microM) resulted in an inhibition of 25-40% of amiloride-sensitive sodium uptake. Moreover, quinidine (10(-4)M) and ruthenium red (3 microM), agents presumed to increase cytosolic calcium, inhibited amiloride-sensitive sodium uptake by 20-60%. Both these agents also inhibited sodium-dependent phosphate uptake by 20% but had no effect on ouabain-sensitive 86Rb+ uptake or on sodium-dependent alpha-methylglucoside uptake. Our data indicate that increases in extracellular calcium inhibit amiloride-sensitive sodium uptake and increases in cytosolic calcium inhibit sodium-dependent phosphate and amiloride-sensitive sodium uptakes. The effect of extracellular calcium may be due to charge screening and/or binding to the negatively charged plasma membrane or due to alterations in membrane fluidity. |Amiloride/pharmacology[MESH] |Animals[MESH] |Biological Transport/drug effects[MESH] |Calcimycin/pharmacology[MESH] |Calcium/*pharmacology[MESH] |Cells, Cultured[MESH] |Cytosol/metabolism[MESH] |Kidney Tubules, Proximal/*metabolism[MESH] |Kinetics[MESH] |Male[MESH] |Methylglucosides/metabolism[MESH] |Ouabain/pharmacology[MESH] |Phosphates/metabolism[MESH] |Rabbits[MESH] |Rubidium/metabolism[MESH]Effect of calcium on transport characteristics of cultured proximal re(epmc).pdf DeepDyve Pubget Overpricing