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10.1016/j.heliyon.2024.e25595 http://scihub22266oqcxt.onion/10.1016/j.heliyon.2024.e25595 38356581!10865327!38356581     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=38356581&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Heliyon 2024 ; 10 (3): e25595 Nephropedia Template TP {{tp|p=38356581|t=2024. The effect of adoptive transferring myeloid-derived suppressor cells in ventilator-induced lung injury mice |pdf=|usr=}}{{38356581}} gab.com Text The effect of adoptive transferring myeloid-derived suppressor cells in ventilator-induced lung injury mice JO: Heliyon http://www.kidney.de/pget.php?&tw=1&pmid=38356581 #FOAvip The effects of adoptive transferring myeloid-derived suppressor cells (MDSCs) to mice with ventilator-induced lung injury (VILI) are unclear. Our objective was to investigate the effects of adoptively transferring MDSCs in VILI. The mouse model was created by introducing mechanical ventilation through a high tidal volume of 20 ml/kg for 4 h. Inflammation-induced MDSCs (iMDSCs) were collected from the bone marrow of mice with cecal ligation and puncture. iMDSCs were administrated through retrobulbar angular vein 1 h before the mechanical ventilation. The control group was anesthetized and maintained spontaneous respiration. After the termination of mechanical ventilation, bronchoalveolar lavage fluid (BALF) and lung samples 6 h were collected. The concentrations of BALF protein, levels of inflammatory mediators, and white blood cells were all significantly decreased in mice treated with iMDSCs. Histological examinations indicated reduced lung damage after iMDSCs treatment. Moreover, adoptive transfer of iMDSCs could reduce CD4(+) T-cell counts and inhibit its inflammatory cytokine secretion. iMDSCs treatment was found to had no immunostimulatory effects or cause secondary infections in mice. In conclusion, MDSCs might be a potential targeted therapy for alleviating the inflammatory response of VILI mice in a T-cell dependent manner. Twit Text FOAVip The effect of adoptive transferring myeloid-derived suppressor cells in ventilator-induced lung injury mice ????Heliyon http://www.kidney.de/pget.php?&tw=1&pmid=38356581 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=38356581 #FOAvip English Wikipedia <ref>{{Cite pmid|38356581}}</ref> The effect of adoptive transferring myeloid-derived suppressor cells in ventilator-induced lung injury mice #MMPMID38356581 Shan F; Tang F; Liu Y; Han X; Wu W; Tang Y; Zhan Q; Zhang N Heliyon 2024[Feb]; 10 (3): e25595 PMID38356581show ga The effects of adoptive transferring myeloid-derived suppressor cells (MDSCs) to mice with ventilator-induced lung injury (VILI) are unclear. Our objective was to investigate the effects of adoptively transferring MDSCs in VILI. The mouse model was created by introducing mechanical ventilation through a high tidal volume of 20 ml/kg for 4 h. Inflammation-induced MDSCs (iMDSCs) were collected from the bone marrow of mice with cecal ligation and puncture. iMDSCs were administrated through retrobulbar angular vein 1 h before the mechanical ventilation. The control group was anesthetized and maintained spontaneous respiration. After the termination of mechanical ventilation, bronchoalveolar lavage fluid (BALF) and lung samples 6 h were collected. The concentrations of BALF protein, levels of inflammatory mediators, and white blood cells were all significantly decreased in mice treated with iMDSCs. Histological examinations indicated reduced lung damage after iMDSCs treatment. Moreover, adoptive transfer of iMDSCs could reduce CD4(+) T-cell counts and inhibit its inflammatory cytokine secretion. iMDSCs treatment was found to had no immunostimulatory effects or cause secondary infections in mice. In conclusion, MDSCs might be a potential targeted therapy for alleviating the inflammatory response of VILI mice in a T-cell dependent manner. ?The effect of adoptive transferring myeloid-derived suppressor cells i(epmc).pdf DeepDyve Pubget Overpricing