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10.1099/0022-1317-68-2-419 http://scihub22266oqcxt.onion/10.1099/0022-1317-68-2-419 3819695!ä!3819695 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Gen+Virol 1987 ; 68 ( Pt 2) (ä): 419-24 Nephropedia Template TP {{tp|p=3819695|t=1987. Mechanism of protection during the early phase of a generalized viral infection II Contribution of polymorphonuclear leukocytes to protection against intravenous infection with influenza virus |pdf=|usr=}}{{3819695}} gab.com Text Mechanism of protection during the early phase of a generalized viral infection II Contribution of polymorphonuclear leukocytes to protection against intravenous infection with influenza virus JO: J Gen Virol http://www.kidney.de/pget.php?&tw=1&pmid=3819695 #FOAvip The contribution of phagocytes to the early protection of mice inoculated intravenously with influenza virus was investigated in phagocyte-depleted mice. Following the inoculation of a sublethal dose of influenza virus, virus titres in the liver and lung of both untreated and carrageenan-treated mice were reduced rapidly by day 1 and decreased slowly to reach an undetectable level by day 7. The titres in gamma-irradiated mice decreased transiently by day 1 and increased progressively thereafter to kill all of the hosts by day 8. The clearance of virus from blood at the early stage of infection was retarded by gamma-irradiation but not by carrageenan treatment. In addition, increase in virus titres in the liver and lung in the early stage of the infection was prevented by adoptive transfer with syngeneic polymorphonuclear leukocytes into gamma-irradiated mice. No significant rise of neutralizing antibody was detectable by day 3 after the inoculation, in any of the three groups of mice. These observations imply that gamma-sensitive and carrageenan-resistant polymorphonuclear leukocytes play a protective role at the early stage in the infection, whereas fixed macrophages or natural killer cells, both of which are carrageenan-sensitive and gamma-resistant, scarcely participate in the early phase. Twit Text FOAVip Mechanism of protection during the early phase of a generalized viral infection II Contribution of polymorphonuclear leukocytes to protection against intravenous infection with influenza virus ????J Gen Virol http://www.kidney.de/pget.php?&tw=1&pmid=3819695 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=3819695 #FOAvip English Wikipedia <ref>{{Cite pmid|3819695}}</ref> Mechanism of protection during the early phase of a generalized viral infection II Contribution of polymorphonuclear leukocytes to protection against intravenous infection with influenza virus #MMPMID3819695 Tsuru S; Fujisawa H; Taniguchi M; Zinnaka Y; Nomoto K J Gen Virol 1987[Feb]; 68 ( Pt 2) (ä): 419-24 PMID3819695show ga The contribution of phagocytes to the early protection of mice inoculated intravenously with influenza virus was investigated in phagocyte-depleted mice. Following the inoculation of a sublethal dose of influenza virus, virus titres in the liver and lung of both untreated and carrageenan-treated mice were reduced rapidly by day 1 and decreased slowly to reach an undetectable level by day 7. The titres in gamma-irradiated mice decreased transiently by day 1 and increased progressively thereafter to kill all of the hosts by day 8. The clearance of virus from blood at the early stage of infection was retarded by gamma-irradiation but not by carrageenan treatment. In addition, increase in virus titres in the liver and lung in the early stage of the infection was prevented by adoptive transfer with syngeneic polymorphonuclear leukocytes into gamma-irradiated mice. No significant rise of neutralizing antibody was detectable by day 3 after the inoculation, in any of the three groups of mice. These observations imply that gamma-sensitive and carrageenan-resistant polymorphonuclear leukocytes play a protective role at the early stage in the infection, whereas fixed macrophages or natural killer cells, both of which are carrageenan-sensitive and gamma-resistant, scarcely participate in the early phase. |Animals[MESH] |Antibodies, Viral/immunology[MESH] |Carrageenan/pharmacology[MESH] |Female[MESH] |Gamma Rays[MESH] |Immunization, Passive[MESH] |Influenza A virus/isolation & purification[MESH] |Injections, Intravenous[MESH] |Liver/microbiology[MESH] |Lung/microbiology[MESH] |Mice[MESH] |Mice, Inbred BALB C[MESH] |Neutrophils/*physiology[MESH] |Orthomyxoviridae Infections/*immunology/microbiology[MESH] |Phagocytes/physiology[MESH] |Phagocytosis/drug effects/radiation effects[MESH]Mechanism of protection during the early phase of a generalized viral (epmc).pdf DeepDyve Pubget Overpricing