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10.1177/030006058601400404

http://scihub22266oqcxt.onion/10.1177/030006058601400404
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3758469!ä!3758469

suck abstract from ncbi


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pmid3758469      J+Int+Med+Res 1986 ; 14 (4): 188-92
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  • Comparison of the diuretic effects of single dose frusemide/triamterene and hydrochlorothiazide/amiloride in healthy adults #MMPMID3758469
  • Kohvakka A; Hussi E
  • J Int Med Res 1986[]; 14 (4): 188-92 PMID3758469show ga
  • The diuretic and potassium- and magnesium-conserving action of a single dose of frusemide/triamterene, F + TRI (40 mg/50 mg), and hydrochlorothiazide/amiloride, HCT + AMI (50 mg/5 mg), fixed combination preparations were compared in ten healthy adults in a randomised double-blind placebo-controlled study. Urinary volume during 24 hours was significantly higher after HCT + AMI ingestion than after F + TRI. The urine and sodium excretions caused by HCT + AMI lasted markedly longer and were smoother than the short and somewhat unpleasant effects of F + TRI. HCT + AMI also spared potassium and magnesium relatively more effectively than F + TRI.
  • |Adult[MESH]
  • |Amiloride/*pharmacology[MESH]
  • |Double-Blind Method[MESH]
  • |Drug Combinations[MESH]
  • |Furosemide/*pharmacology[MESH]
  • |Hematocrit[MESH]
  • |Humans[MESH]
  • |Hydrochlorothiazide/*pharmacology[MESH]
  • |Magnesium/urine[MESH]
  • |Male[MESH]
  • |Potassium/urine[MESH]
  • |Sodium/urine[MESH]
  • |Time Factors[MESH]
  • |Triamterene/*pharmacology[MESH]


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