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10.1093/ageing/15.3.151

http://scihub22266oqcxt.onion/10.1093/ageing/15.3.151
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3739851!ä!3739851

suck abstract from ncbi


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pmid3739851      Age+Ageing 1986 ; 15 (3): 151-5
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  • The metabolic effects of thiazide therapy in the elderly: a population study #MMPMID3739851
  • Petri M; Cumber P; Grimes L; Treby D; Bryant R; Rawlins D; Ising H
  • Age Ageing 1986[May]; 15 (3): 151-5 PMID3739851show ga
  • The metabolic consequences of thiazide diuretics are well known. The elderly to whom these agents are widely prescribed may be particularly susceptible. To quantify this metabolic risk, plasma and intracellular electrolytes and plasma glucose were measured in the elderly population of a Somerset village. Highly significant reductions in both plasma and cellular magnesium and potassium were found in the 47 thiazide-treated people. Forty-eight per cent of the thiazide-treated group were hypomagnesaemic and 28% were hypokalaemic. Thus, magnesium and potassium depletion are commonly associated with thiazide therapy in the elderly. These metabolic effects should be considered carefully prior to the use of these agents.
  • |Aged[MESH]
  • |Bendroflumethiazide/*adverse effects/therapeutic use[MESH]
  • |Blood Glucose[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Hypokalemia/chemically induced[MESH]
  • |Magnesium/*blood[MESH]
  • |Male[MESH]
  • |Potassium/*blood[MESH]


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