Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1159/000526244 http://scihub22266oqcxt.onion/10.1159/000526244 36817291!9936767!36817291     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=36817291&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Glomerular+Dis 2022 ; 2 (4): 153-163 Nephropedia Template TP {{tp|p=36817291|t=2022. Monoclonal Gammopathy of Renal Significance: Histomorphological Spectrum at a Tertiary Care Center |pdf=|usr=}}{{36817291}} gab.com Text Monoclonal Gammopathy of Renal Significance: Histomorphological Spectrum at a Tertiary Care Center JO: Glomerular Dis http://www.kidney.de/pget.php?&tw=1&pmid=36817291 #FOAvip INTRODUCTION: The term monoclonal gammopathy of renal significance (MGRS) has been described to include patients with renal manifestations associated with circulating monoclonal proteins with or without a clonal lymphoproliferation (B-cell or plasma cell) and not meeting diagnostic criteria for an overt hematological malignancy. A host of MGRS-associated lesions have been described that involve various renal compartments. Our study describes the histomorphological spectrum of MGRS cases at our center in the last 5 years and description as per the classification system of the International Kidney and Monoclonal Gammopathy Research Group (IKMG). MATERIAL AND METHODS: Retrospective analysis was carried out of all the renal biopsies with characteristic monoclonal immunoglobulin lesions for histopathological diagnosis between years 2015 and 2020 and reviewed by two independent pathologists. RESULTS: Most patients in the study belonged to the fifth decade, with a median age of 50 years (mean 50.14 +/- 10.43) range (24-68 years) with a male preponderance. Most patients presented with proteinuria as the sole manifestation (66.6%). Many of the patients (48%) had an M spike by serum protein electrophoresis or urinary protein electrophoresis with an abnormal serum free light chain assay (60.8%). AL amyloidosis was the most common diagnosis observed on histopathological evaluation (68.7%), followed by light chain deposition disease (10.4%). CONCLUSION: MGRS lesions are infrequently encountered in the practice of nephropathology and pose a diagnostic challenge due to the limitation of a congruent clinical or hematological picture. A thorough histological examination with immunofluorescence and electron microscopy often precipitates in the right diagnosis and prompts timely management. Twit Text FOAVip Monoclonal Gammopathy of Renal Significance: Histomorphological Spectrum at a Tertiary Care Center ????Glomerular Dis http://www.kidney.de/pget.php?&tw=1&pmid=36817291 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=36817291 #FOAvip English Wikipedia <ref>{{Cite pmid|36817291}}</ref> Monoclonal Gammopathy of Renal Significance: Histomorphological Spectrum at a Tertiary Care Center #MMPMID36817291 Barwad A; Bajaj V; Singh G; Dinda AK; Sahoo RK; Kumar L; Agarwal SK Glomerular Dis 2022[]; 2 (4): 153-163 PMID36817291show ga INTRODUCTION: The term monoclonal gammopathy of renal significance (MGRS) has been described to include patients with renal manifestations associated with circulating monoclonal proteins with or without a clonal lymphoproliferation (B-cell or plasma cell) and not meeting diagnostic criteria for an overt hematological malignancy. A host of MGRS-associated lesions have been described that involve various renal compartments. Our study describes the histomorphological spectrum of MGRS cases at our center in the last 5 years and description as per the classification system of the International Kidney and Monoclonal Gammopathy Research Group (IKMG). MATERIAL AND METHODS: Retrospective analysis was carried out of all the renal biopsies with characteristic monoclonal immunoglobulin lesions for histopathological diagnosis between years 2015 and 2020 and reviewed by two independent pathologists. RESULTS: Most patients in the study belonged to the fifth decade, with a median age of 50 years (mean 50.14 +/- 10.43) range (24-68 years) with a male preponderance. Most patients presented with proteinuria as the sole manifestation (66.6%). Many of the patients (48%) had an M spike by serum protein electrophoresis or urinary protein electrophoresis with an abnormal serum free light chain assay (60.8%). AL amyloidosis was the most common diagnosis observed on histopathological evaluation (68.7%), followed by light chain deposition disease (10.4%). CONCLUSION: MGRS lesions are infrequently encountered in the practice of nephropathology and pose a diagnostic challenge due to the limitation of a congruent clinical or hematological picture. A thorough histological examination with immunofluorescence and electron microscopy often precipitates in the right diagnosis and prompts timely management. ?Monoclonal Gammopathy of Renal Significance: Histomorphological Spectr(epmc).pdf DeepDyve Pubget Overpricing