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10.3390/ijms24032976 http://scihub22266oqcxt.onion/10.3390/ijms24032976 36769304!9917990!36769304     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=36769304&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Int+J+Mol+Sci 2023 ; 24 (3): ? Nephropedia Template TP {{tp|p=36769304|t=2023. The Functional Meaning of 5 UTR in Protein-Coding Genes |pdf=|usr=}}{{36769304}} gab.com Text The Functional Meaning of 5 UTR in Protein-Coding Genes JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=36769304 #FOAvip As it is well known, messenger RNA has many regulatory regions along its sequence length. One of them is the 5' untranslated region (5'UTR), which itself contains many regulatory elements such as upstream ORFs (uORFs), internal ribosome entry sites (IRESs), microRNA binding sites, and structural components involved in the regulation of mRNA stability, pre-mRNA splicing, and translation initiation. Activation of the alternative, more upstream transcription start site leads to an extension of 5'UTR. One of the consequences of 5'UTRs extension may be head-to-head gene overlap. This review describes elements in 5'UTR of protein-coding transcripts and the functional significance of protein-coding genes 5' overlap with implications for transcription, translation, and disease. Twit Text FOAVip The Functional Meaning of 5 UTR in Protein-Coding Genes ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=36769304 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=36769304 #FOAvip English Wikipedia <ref>{{Cite pmid|36769304}}</ref> The Functional Meaning of 5 UTR in Protein-Coding Genes #MMPMID36769304 Ryczek N; Lys A; Makalowska I Int J Mol Sci 2023[Feb]; 24 (3): ? PMID36769304show ga As it is well known, messenger RNA has many regulatory regions along its sequence length. One of them is the 5' untranslated region (5'UTR), which itself contains many regulatory elements such as upstream ORFs (uORFs), internal ribosome entry sites (IRESs), microRNA binding sites, and structural components involved in the regulation of mRNA stability, pre-mRNA splicing, and translation initiation. Activation of the alternative, more upstream transcription start site leads to an extension of 5'UTR. One of the consequences of 5'UTRs extension may be head-to-head gene overlap. This review describes elements in 5'UTR of protein-coding transcripts and the functional significance of protein-coding genes 5' overlap with implications for transcription, translation, and disease. |*Gene Expression Regulation[MESH] |*Protein Biosynthesis[MESH] |5' Untranslated Regions[MESH] |RNA, Messenger/genetics[MESH]The Functional Meaning of 5 UTR in Protein-Coding Genes (epmc).pdf DeepDyve Pubget Overpricing