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10.3390/v14081608 http://scihub22266oqcxt.onion/10.3390/v14081608 35893674!9394478!35893674     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2022 ; 14 (8): ä Nephropedia Template TP {{tp|p=35893674|t=2022. Nasal Mucosa Exploited by SARS-CoV-2 for Replicating and Shedding during Reinfection |pdf=|usr=}}{{35893674}} gab.com Text Nasal Mucosa Exploited by SARS-CoV-2 for Replicating and Shedding during Reinfection JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=35893674 #FOAvip Reinfection risk is a great concern with regard to the COVID-19 pandemic because a large proportion of the population has recovered from an initial infection, and previous reports found that primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques without viral presence and pathological injury; however, a high possibility for reinfection at the current stage of the pandemic has been proven. We found the reinfection of SARS-CoV-2 in Syrian hamsters with continuous viral shedding in the upper respiratory tracts and few injuries in the lung, and nasal mucosa was exploited by SARS-CoV-2 for replication and shedding during reinfection; meanwhile, no viral replication or enhanced damage was observed in the lower respiratory tracts. Consistent with the mild phenotype in the reinfection, increases in mRNA levels in cytokines and chemokines in the nasal mucosa but only slight increases in the lung were found. Notably, the high levels of neutralizing antibodies in serum could not prevent reinfection in hamsters but may play roles in benefitting the lung recovery and symptom relief of COVID-19. In summary, Syrian hamsters could be reinfected by SARS-CoV-2 with mild symptoms but with obvious viral shedding and replication, and both convalescent and vaccinated patients should be wary of the transmission and reinfection of SARS-CoV-2. Twit Text FOAVip Nasal Mucosa Exploited by SARS-CoV-2 for Replicating and Shedding during Reinfection ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=35893674 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35893674 #FOAvip English Wikipedia <ref>{{Cite pmid|35893674}}</ref> Nasal Mucosa Exploited by SARS-CoV-2 for Replicating and Shedding during Reinfection #MMPMID35893674 Li H; Zhao X; Li J; Zheng H; Zhao Y; Yang J; Zhou J; Yang F; Chen Y; Zuo Y; Lai Q; Long H; Li Y; Jin W; Shi H; Liu L Viruses 2022[Jul]; 14 (8): ä PMID35893674show ga Reinfection risk is a great concern with regard to the COVID-19 pandemic because a large proportion of the population has recovered from an initial infection, and previous reports found that primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques without viral presence and pathological injury; however, a high possibility for reinfection at the current stage of the pandemic has been proven. We found the reinfection of SARS-CoV-2 in Syrian hamsters with continuous viral shedding in the upper respiratory tracts and few injuries in the lung, and nasal mucosa was exploited by SARS-CoV-2 for replication and shedding during reinfection; meanwhile, no viral replication or enhanced damage was observed in the lower respiratory tracts. Consistent with the mild phenotype in the reinfection, increases in mRNA levels in cytokines and chemokines in the nasal mucosa but only slight increases in the lung were found. Notably, the high levels of neutralizing antibodies in serum could not prevent reinfection in hamsters but may play roles in benefitting the lung recovery and symptom relief of COVID-19. In summary, Syrian hamsters could be reinfected by SARS-CoV-2 with mild symptoms but with obvious viral shedding and replication, and both convalescent and vaccinated patients should be wary of the transmission and reinfection of SARS-CoV-2. |*COVID-19[MESH] |*SARS-CoV-2[MESH] |Animals[MESH] |Cricetinae[MESH] |Disease Models, Animal[MESH] |Humans[MESH] |Macaca mulatta[MESH] |Mesocricetus[MESH] |Nasal Mucosa[MESH] |Pandemics[MESH]Nasal Mucosa Exploited by SARS-CoV-2 for Replicating and Shedding duri(epmc).pdf DeepDyve Pubget Overpricing