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10.3389/fimmu.2022.879792 http://scihub22266oqcxt.onion/10.3389/fimmu.2022.879792 35860279!9290522!35860279     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2022 ; 13 (ä): 879792 Nephropedia Template TP {{tp|p=35860279|t=2022. Pathogenic Mechanism and Multi-omics Analysis of Oral Manifestations in COVID-19 |pdf=|usr=}}{{35860279}} gab.com Text Pathogenic Mechanism and Multi-omics Analysis of Oral Manifestations in COVID-19 JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=35860279 #FOAvip Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease that seriously threatens human life. The clinical manifestations of severe COVID-19 include acute respiratory distress syndrome and multiple organ failure. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, spreads through contaminated droplets. SARS-CoV-2 particles have been detected in the saliva of COVID-19 patients, implying that the virus can infect and damage the oral cavity. The oral manifestations of COVID-19 include xerostomia and gustatory dysfunction. Numerous studies showed that the four structural proteins of SARS-CoV-2 are its potential pathogenic factors, especially the S protein, which binds to human ACE2 receptors facilitating the entry of the virus into the host cells. Usually, upon entry into the host cell, a pathogen triggers the host's immune response. However, a mount of multi-omics and immunological analyses revealed that COVID-19 is caused by immune dysregulation. A decrease in the number and phenotypes of immune cells, IFN-1 production and excessive release of certain cytokines have also been reported. In conclusion, this review summarizes the oral manifestations of COVID-19 and multi-omics analysis of SARS-CoV-2 infection. Twit Text FOAVip Pathogenic Mechanism and Multi-omics Analysis of Oral Manifestations in COVID-19 ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=35860279 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35860279 #FOAvip English Wikipedia <ref>{{Cite pmid|35860279}}</ref> Pathogenic Mechanism and Multi-omics Analysis of Oral Manifestations in COVID-19 #MMPMID35860279 Hao M; Wang D; Xia Q; Kan S; Chang L; Liu H; Yang Z; Liu W Front Immunol 2022[]; 13 (ä): 879792 PMID35860279show ga Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease that seriously threatens human life. The clinical manifestations of severe COVID-19 include acute respiratory distress syndrome and multiple organ failure. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, spreads through contaminated droplets. SARS-CoV-2 particles have been detected in the saliva of COVID-19 patients, implying that the virus can infect and damage the oral cavity. The oral manifestations of COVID-19 include xerostomia and gustatory dysfunction. Numerous studies showed that the four structural proteins of SARS-CoV-2 are its potential pathogenic factors, especially the S protein, which binds to human ACE2 receptors facilitating the entry of the virus into the host cells. Usually, upon entry into the host cell, a pathogen triggers the host's immune response. However, a mount of multi-omics and immunological analyses revealed that COVID-19 is caused by immune dysregulation. A decrease in the number and phenotypes of immune cells, IFN-1 production and excessive release of certain cytokines have also been reported. In conclusion, this review summarizes the oral manifestations of COVID-19 and multi-omics analysis of SARS-CoV-2 infection. |*COVID-19[MESH] |Humans[MESH] |Peptidyl-Dipeptidase A/metabolism[MESH]Pathogenic Mechanism and Multi-omics Analysis of Oral Manifestations i(epmc).pdf DeepDyve Pubget Overpricing