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10.1177/03946320221115316

http://scihub22266oqcxt.onion/10.1177/03946320221115316
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suck abstract from ncbi


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pmid35840546      Int+J+Immunopathol+Pharmacol 2022 ; 36 (ä): 3946320221115316
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  • COVID-19: Clinical laboratory diagnosis and monitoring of novel coronavirus infected patients using molecular, serological and biochemical markers: A review #MMPMID35840546
  • Rasool G; Riaz M; Abbas M; Fatima H; Qamar MM; Zafar F; Mahmood Z
  • Int J Immunopathol Pharmacol 2022[Jan]; 36 (ä): 3946320221115316 PMID35840546show ga
  • COVID-19, a novel coronavirus disease, has provoked a variety of health and safety concerns, and socioeconomic challenges around the globe. The laboratory diagnosis of SARS-CoV-2 was quickly established utilizing nucleic acid amplification techniques (NAAT) after the disease causing virus has been identified, and its genetic sequence has been determined. In addition to NAAT, serological tests based on antibodies testing against SARS-CoV-2 were introduced for diagnostic and epidemiologic studies. Other biochemical investigations include monitoring of peripheral blood cells count, platelets/lymphocyte ratio, coagulation profile, cardiac, and inflammatory markers such as cytokines storm are also crucial in combating COVID-19 pandemic. Further, accurate and reliable laboratory results for SARS-CoV-2 play very important role in the initiation of early treatment and timely management of COVID-19 patients, provide support in clinical decision-making process to control infection, and detection of asymptomatic cases. The Task Force on Coronavirus-19 constituted by International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) has recognized informational framework for epidemiology, pathogenesis, and recommended the PCR-based analysis, serological and biochemical assays for analysis, monitoring, and management of disease. This literature review provides an overview of the currently used diagnostic techniques in clinical laboratories for the diagnosis, treatment monitoring, and management of COVID-19 patients. We concluded that each assays differ in their performance characteristics and the utilization of multiple techniques is necessary for the accurate diagnosis and management of SARS-CoV-2 infection.
  • |*COVID-19/diagnosis[MESH]
  • |*SARS-CoV-2[MESH]
  • |Biomarkers[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Humans[MESH]
  • |Laboratories, Clinical[MESH]


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