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Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Clin+Med 2022 ; 11 (13): ä Nephropedia Template TP
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Collapsing Glomerulonephritis in a Kidney Transplant Recipient after mRNA SARS-CoV-2 Vaccination #MMPMID35806939
Gomez Preciado F; De Carvalho Ovalles RA; Codina S; Donadeu L; Fava A; Martinez Valenzuela L; Sandoval D; Fernandez-Cidon B; Bestard O; Alia-Ramos P; Goma M; Melilli E; Cruzado JM
J Clin Med 2022[Jun]; 11 (13): ä PMID35806939show ga
With the vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), studies are describing cases of glomerulonephritis arising after vaccination. We present the first case of a kidney transplant patient who, after mRNA vaccination against SARS-CoV-2, developed nephrotic proteinuria and renal dysfunction, with a biopsy diagnostic of collapsing glomerulonephritis. No other triggers for this glomerulonephritis were identified. Antibodies against the spike protein were negative, but the patient developed a specific T-cell response. The close time between vaccination and the proteinuria suggests a possible determinant role of vaccination. We should be aware of nephropathies appearing after COVID-19 vaccination in kidney transplant recipients also.