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10.1016/j.ijid.2022.06.057

http://scihub22266oqcxt.onion/10.1016/j.ijid.2022.06.057
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suck abstract from ncbi


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pmid35803468      Int+J+Infect+Dis 2022 ; 122 (ä): 543-549
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  • Hypermagnesemia and hyperphosphatemia are highly prevalent in patients with COVID-19 and increase the risk of death #MMPMID35803468
  • Malinowska J; Malecka-Gieldowska M; Bankowska D; Borecka K; Ciepiela O
  • Int J Infect Dis 2022[Sep]; 122 (ä): 543-549 PMID35803468show ga
  • OBJECTIVES: Nonrespiratory manifestations of COVID-19 include endocrine disorders, among which are calcium-magnesium-phosphate homeostasis abnormalities, which seem to influence the disease severity and patient outcome. The aim of this study was to evaluate the prevalence and impact of calcium-magnesium-phosphate and vitamin D3 disorders on survival in patients hospitalized for COVID-19 depending on the severity of the disease and kidney function. DESIGN OR METHODS: The study was conducted between April 2020 and May 2021 at Central Clinical Hospital in Warsaw, Poland. A total of 146 patients who had tested concentration of at least one of the studied elements, estimated glomerular filtration ratio, creatinine levels, and blood saturation, and were diagnosed with COVID-19 disease were included in the analysis. RESULTS: We found that hypermagnesemia was common and associated with a 1.5-fold increased risk of death in the whole cohort. Hyperphosphatemia also increased the risk of death, exactly 2.4-fold. Furthermore, we found a statistically significant association between increased mortality in the whole cohort and hypovitaminosis D3 (P <0.05). Serum creatinine concentration and estimated glomerular filtration ratio significantly correlated with serum magnesium and phosphate levels. CONCLUSION: Hypermagnesemia, hyperphosphatemia, and hypovitaminosis D but not hypocalcemia influence the mortality of patients with COVID-19. These parameters should be monitored routinely in this group of patients, especially in those with decreased kidney function.
  • |*COVID-19/complications[MESH]
  • |*Hyperphosphatemia/complications[MESH]
  • |*Metabolic Diseases/diagnosis/etiology[MESH]
  • |Calcium[MESH]
  • |Humans[MESH]
  • |Magnesium[MESH]


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