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10.4081/monaldi.2022.2281

http://scihub22266oqcxt.onion/10.4081/monaldi.2022.2281
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35754393!ä!35754393

suck abstract from ncbi


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pmid35754393      Monaldi+Arch+Chest+Dis 2022 ; 93 (1): ä
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  • Tuberculosis endemicity and BCG vaccination: Protection against COVID-19 #MMPMID35754393
  • Boppana TK; Mittal S; Madan K; Mohan A; Hadda V; Guleria R
  • Monaldi Arch Chest Dis 2022[Jun]; 93 (1): ä PMID35754393show ga
  • The coronavirus disease 2019 (COVID-19) has affected different countries in a differential manner. The host susceptibility and host factors are important parameters for this variability. This study aimed to assess the effect of tuberculosis (TB) endemicity and Bacille Calmette-Guerin (BCG) coverage on COVID-19. Available data regarding TB incidence, BCG coverage (as per the World Health Organization), and COVID-19 incidence of 168 countries as of 19th September 2021was collected. Countries were divided into four cohorts based upon annual TB incidence and BCG coverage and COVID-19 incidence and case fatality rates were compared using the Kruskal-Wallis test. Countries with low TB incidence and low BCG coverage had the highest COVID-19 incidence per lac population. However, no significant difference was seen in COVID-19 cases fatality rate. Higher TB incidence and BCG coverage were associated with lesser incidence of COVID-19. This result paves the way for research into pathogenesis and host immune response in COVID-19.
  • |*COVID-19/epidemiology/prevention & control[MESH]
  • |*Tuberculosis/epidemiology/prevention & control[MESH]
  • |BCG Vaccine/therapeutic use[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]


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