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10.1002/eji.202249827

http://scihub22266oqcxt.onion/10.1002/eji.202249827
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35689332!9350042!35689332
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suck abstract from ncbi


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pmid35689332      Eur+J+Immunol 2022 ; 52 (10): 1676-1679
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  • COVID-19 rapidly increases MDSCs and prolongs innate immune dysfunctions #MMPMID35689332
  • Schrijver IT; Theroude C; Antonakos N; Regina J; Le Roy D; Bart PA; Chiche JD; Perreau M; Pantaleo G; Calandra T; Roger T
  • Eur J Immunol 2022[Oct]; 52 (10): 1676-1679 PMID35689332show ga
  • We used unsupervised immunophenotyping of blood leukocytes and measured cytokine production by innate immune cell exposed to LPS and R848. We show that COVID-19 induces a rapid, transient upregulation of myeloid-derived suppressor cells (MDSCs) accompanied by a rapid, sustained (up to 3 months) hyporesponsiveness of dendritic cells and monocytes. Blood MDSCs may represent biomarkers and targets for intervention strategies in COVID-19 patients.
  • |*COVID-19[MESH]
  • |*Immune System Diseases[MESH]
  • |*Myeloid-Derived Suppressor Cells[MESH]
  • |Biomarkers[MESH]
  • |Cytokines/pharmacology[MESH]
  • |Humans[MESH]
  • |Immunity, Innate[MESH]


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