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10.1016/j.drudis.2022.06.001

http://scihub22266oqcxt.onion/10.1016/j.drudis.2022.06.001
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35667629!9162932!35667629
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suck abstract from ncbi


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pmid35667629      Drug+Discov+Today 2022 ; 27 (9): 2411-2414
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  • Multiple deadlocks in the development of nonprofit drugs #MMPMID35667629
  • Cvek B
  • Drug Discov Today 2022[Sep]; 27 (9): 2411-2414 PMID35667629show ga
  • The current Coronavirus 2019 (COVID-19) pandemic has shown us that the pharmaceutical research community can organize and administer large nonprofit clinical trials (RECOVERY and SOLIDARITY) and achieve the swift development of common, unpatentable drugs for a new indication: in this case an old, inexpensive drug, dexamethasone, for COVID-19. Why is it that such nonprofit efforts are so rare and are not organized as a systemic, routine part of drug development in the public interest? Based on my own experience with repurposing the alcohol-abuse drug disulfiram (Antabuse) for cancer, I identify at least four serious deadlocks to development of nonprofit drugs. All of these obstacles should be addressed to leverage the potential of the COVID-19 pandemic for better future healthcare systems in all countries around the world.
  • |*COVID-19[MESH]
  • |*Pandemics[MESH]
  • |Delivery of Health Care[MESH]
  • |Disulfiram[MESH]
  • |Humans[MESH]


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