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10.1016/j.acthis.2022.151908 http://scihub22266oqcxt.onion/10.1016/j.acthis.2022.151908 35662001!9130726!35662001     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\35662001.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Acta+Histochem 2022 ; 124 (5): 151908 Nephropedia Template TP {{tp|p=35662001|t=2022. Molecular signaling pathways, pathophysiological features in various organs, and treatment strategies in SARS-CoV2 infection |pdf=|usr=}}{{35662001}} gab.com Text Molecular signaling pathways, pathophysiological features in various organs, and treatment strategies in SARS-CoV2 infection JO: Acta Histochem http://www.kidney.de/pget.php?&tw=1&pmid=35662001 #FOAvip Cytokine storms and extra-activated cytokine signaling pathways can lead to severe tissue damage and patient death. Activation of inflammatory signaling pathways during Cytokine storms are an important factor in the development of acute respiratory syndrome (SARS-CoV-2), which is the major health problem today, causing systemic and local inflammation. Cytokine storms attract many inflammatory cells that attack the lungs and other organs and cause tissue damage. Angiotensin-converting enzyme 2 (ACE2) are expressed in a different type of tissues. inhibition of ACE2 activity impairs renin-angiotensin (RAS) function, which is related to the severity of symptoms and mortality rate in COVID-19 patients. Different signaling cascades are activated, affecting various organs during SARS-CoV-2 infection. Nowadays, there is no specific treatment for COVID-19, but scientists have recognized and proposed several treatment alternatives, including applying cytokine inhibitors, immunomodulators, and plasma therapy. Herein, we have provided the detailed mechanism of SARS-CoV-2 induced cytokine signaling and its connection with pathophysiological features in different organs. Possible treatment options to cope with the severe clinical manifestations of COVID-19 are also discussed. Twit Text FOAVip Molecular signaling pathways, pathophysiological features in various organs, and treatment strategies in SARS-CoV2 infection ????Acta Histochem http://www.kidney.de/pget.php?&tw=1&pmid=35662001 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35662001 #FOAvip English Wikipedia <ref>{{Cite pmid|35662001}}</ref> Molecular signaling pathways, pathophysiological features in various organs, and treatment strategies in SARS-CoV2 infection #MMPMID35662001 Rasmi Y; Hatamkhani S; Naderi R; Shokati A; Nayeb Zadeh V; Hosseinzadeh F; Farnamian Y; Jalali L Acta Histochem 2022[Jul]; 124 (5): 151908 PMID35662001show ga Cytokine storms and extra-activated cytokine signaling pathways can lead to severe tissue damage and patient death. Activation of inflammatory signaling pathways during Cytokine storms are an important factor in the development of acute respiratory syndrome (SARS-CoV-2), which is the major health problem today, causing systemic and local inflammation. Cytokine storms attract many inflammatory cells that attack the lungs and other organs and cause tissue damage. Angiotensin-converting enzyme 2 (ACE2) are expressed in a different type of tissues. inhibition of ACE2 activity impairs renin-angiotensin (RAS) function, which is related to the severity of symptoms and mortality rate in COVID-19 patients. Different signaling cascades are activated, affecting various organs during SARS-CoV-2 infection. Nowadays, there is no specific treatment for COVID-19, but scientists have recognized and proposed several treatment alternatives, including applying cytokine inhibitors, immunomodulators, and plasma therapy. Herein, we have provided the detailed mechanism of SARS-CoV-2 induced cytokine signaling and its connection with pathophysiological features in different organs. Possible treatment options to cope with the severe clinical manifestations of COVID-19 are also discussed. |*Angiotensin-Converting Enzyme 2[MESH] |*COVID-19 Drug Treatment[MESH] |Cytokine Release Syndrome/drug therapy[MESH] |Cytokines/metabolism[MESH] |Humans[MESH] |Renin-Angiotensin System/physiology[MESH] |SARS-CoV-2[MESH]Molecular signaling pathways, pathophysiological features in various o(epmc).pdf DeepDyve Pubget Overpricing