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10.3390/v14050910

http://scihub22266oqcxt.onion/10.3390/v14050910
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35632654!9146233!35632654
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suck abstract from ncbi


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pmid35632654      Viruses 2022 ; 14 (5): ä
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  • Associations and Disease-Disease Interactions of COVID-19 with Congenital and Genetic Disorders: A Comprehensive Review #MMPMID35632654
  • Hromic-Jahjefendic A; Barh D; Ramalho Pinto CH; Gabriel Rodrigues Gomes L; Picanco Machado JL; Afolabi OO; Tiwari S; Aljabali AAA; Tambuwala MM; Serrano-Aroca A; Redwan EM; Uversky VN; Lundstrom K
  • Viruses 2022[Apr]; 14 (5): ä PMID35632654show ga
  • Since December 2019, the COVID-19 pandemic, which originated in Wuhan, China, has resulted in over six million deaths worldwide. Millions of people who survived this SARS-CoV-2 infection show a number of post-COVID complications. Although, the comorbid conditions and post-COVID complexities are to some extent well reviewed and known, the impact of COVID-19 on pre-existing congenital anomalies and genetic diseases are only documented in isolated case reports and case series, so far. In the present review, we analyzed the PubMed indexed literature published between December 2019 and January 2022 to understand this relationship from various points of view, such as susceptibility, severity and heritability. Based on our knowledge, this is the first comprehensive review on COVID-19 and its associations with various congenital anomalies and genetic diseases. According to reported studies, some congenital disorders present high-risk for developing severe COVID-19 since these disorders already include some comorbidities related to the structure and function of the respiratory and cardiovascular systems, leading to severe pneumonia. Other congenital disorders rather cause psychological burdens to patients and are not considered high-risk for the development of severe COVID-19 infection.
  • |*COVID-19[MESH]
  • |China[MESH]
  • |Comorbidity[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]


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