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10.1186/s13643-022-01958-9

http://scihub22266oqcxt.onion/10.1186/s13643-022-01958-9
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suck abstract from ncbi


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pmid35550674      Syst+Rev 2022 ; 11 (1): 90
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  • Lessons from past pandemics: a systematic review of evidence-based, cost-effective interventions to suppress COVID-19 #MMPMID35550674
  • Juneau CE; Pueyo T; Bell M; Gee G; Collazzo P; Potvin L
  • Syst Rev 2022[May]; 11 (1): 90 PMID35550674show ga
  • BACKGROUND: In an unparalleled global response, during the COVID-19 pandemic, 90 countries asked 3.9 billion people to stay home. Yet other countries avoided lockdowns and focused on other strategies, like contact tracing. How effective and cost-effective are these strategies? We aimed to provide a comprehensive summary of the evidence on past pandemic controls, with a focus on cost-effectiveness. METHODS: Following PRISMA guidelines, MEDLINE (1946 to April week 2, 2020) and EMBASE (1974 to April 17, 2020) were searched using a range of terms related to pandemic control. Articles reporting on the effectiveness or cost-effectiveness of at least one intervention were included. RESULTS: We found 1653 papers; 62 were included. The effectiveness of hand-washing and face masks was supported by randomized trials. These measures were highly cost-effective. For other interventions, only observational and modelling studies were found. They suggested that (1) the most cost-effective interventions are swift contact tracing and case isolation, surveillance networks, protective equipment for healthcare workers, and early vaccination (when available); (2) home quarantines and stockpiling antivirals are less cost-effective; (3) social distancing measures like workplace and school closures are effective but costly, making them the least cost-effective options; (4) combinations are more cost-effective than single interventions; and (5) interventions are more cost-effective when adopted early. For 2009 H1N1 influenza, contact tracing was estimated to be 4363 times more cost-effective than school closure ($2260 vs. $9,860,000 per death prevented). CONCLUSIONS AND CONTRIBUTIONS: For COVID-19, a cautious interpretation suggests that (1) workplace and school closures are effective but costly, especially when adopted late, and (2) scaling up as early as possible a combination of interventions that includes hand-washing, face masks, ample protective equipment for healthcare workers, and swift contact tracing and case isolation is likely to be the most cost-effective strategy.
  • |*COVID-19/epidemiology/prevention & control[MESH]
  • |*Influenza A Virus, H1N1 Subtype[MESH]
  • |Communicable Disease Control[MESH]
  • |Cost-Benefit Analysis[MESH]
  • |Humans[MESH]
  • |Pandemics/prevention & control[MESH]


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