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10.1016/j.molmed.2022.04.007 http://scihub22266oqcxt.onion/10.1016/j.molmed.2022.04.007 35537987!9021367!35537987     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Mol+Med 2022 ; 28 (7): 542-554 Nephropedia Template TP {{tp|p=35537987|t=2022. Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis |pdf=|usr=}}{{35537987}} gab.com Text Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis JO: Trends Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=35537987 #FOAvip Vaccination is a major tool for mitigating the coronavirus disease 2019 (COVID-19) pandemic, and mRNA vaccines are central to the ongoing vaccination campaign that is undoubtedly saving thousands of lives. However, adverse effects (AEs) following vaccination have been noted which may relate to a proinflammatory action of the lipid nanoparticles used or the delivered mRNA (i.e., the vaccine formulation), as well as to the unique nature, expression pattern, binding profile, and proinflammatory effects of the produced antigens - spike (S) protein and/or its subunits/peptide fragments - in human tissues or organs. Current knowledge on this topic originates mostly from cell-based assays or from model organisms; further research on the cellular/molecular basis of the mRNA vaccine-induced AEs will therefore promise safety, maintain trust, and direct health policies. Twit Text FOAVip Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis ????Trends Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=35537987 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35537987 #FOAvip English Wikipedia <ref>{{Cite pmid|35537987}}</ref> Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis #MMPMID35537987 Trougakos IP; Terpos E; Alexopoulos H; Politou M; Paraskevis D; Scorilas A; Kastritis E; Andreakos E; Dimopoulos MA Trends Mol Med 2022[Jul]; 28 (7): 542-554 PMID35537987show ga Vaccination is a major tool for mitigating the coronavirus disease 2019 (COVID-19) pandemic, and mRNA vaccines are central to the ongoing vaccination campaign that is undoubtedly saving thousands of lives. However, adverse effects (AEs) following vaccination have been noted which may relate to a proinflammatory action of the lipid nanoparticles used or the delivered mRNA (i.e., the vaccine formulation), as well as to the unique nature, expression pattern, binding profile, and proinflammatory effects of the produced antigens - spike (S) protein and/or its subunits/peptide fragments - in human tissues or organs. Current knowledge on this topic originates mostly from cell-based assays or from model organisms; further research on the cellular/molecular basis of the mRNA vaccine-induced AEs will therefore promise safety, maintain trust, and direct health policies. |*COVID-19/prevention & control[MESH] |*Viral Vaccines/genetics[MESH] |Antibodies, Neutralizing[MESH] |Antibodies, Viral[MESH] |COVID-19 Vaccines/adverse effects[MESH] |Humans[MESH] |Liposomes[MESH] |Nanoparticles[MESH] |RNA, Messenger/genetics[MESH] |SARS-CoV-2[MESH] |Spike Glycoprotein, Coronavirus/chemistry/genetics[MESH] |Vaccines, Synthetic[MESH]Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis (epmc).pdf DeepDyve Pubget Overpricing