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10.1016/j.ijid.2022.04.057

http://scihub22266oqcxt.onion/10.1016/j.ijid.2022.04.057
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35500794!9054706!35500794
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suck abstract from ncbi


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pmid35500794      Int+J+Infect+Dis 2022 ; 121 (ä): 98-101
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  • An autopsy case of COVID-19-like acute respiratory distress syndrome after mRNA-1273 SARS-CoV-2 vaccination #MMPMID35500794
  • Yoshimura Y; Sasaki H; Miyata N; Miyazaki K; Okudela K; Tateishi Y; Hayashi H; Kawana-Tachikawa A; Iwashita H; Maeda K; Ihama Y; Hatayama Y; Ryo A; Tachikawa N
  • Int J Infect Dis 2022[Aug]; 121 (ä): 98-101 PMID35500794show ga
  • We report the first case with COVID-19-like acute respiratory distress syndrome after mRNA-1273 SARS-CoV-2 vaccination. An 88-year-old woman developed dyspnea several hours after vaccination with the second dose of mRNA-1273. She was hospitalized on day nine due to worsening dyspnea. Chest computed tomography showed bilateral ground-glass opacities and consolidations, mainly in the peripheral lung areas. Repeat polymerase chain reaction tests for SARS-CoV-2 were negative, although the serum level of antibodies against spike protein was extremely elevated. Her condition did not improve with high-dose corticosteroids and high-flow nasal cannula oxygen therapy; she died on day 18. Autopsy findings revealed very early-phase diffuse alveolar damage in the whole lung without other lung diseases. The clinical and pathological findings suggested vaccine-induced acute respiratory distress syndrome. Serological and pathological tests might be useful to differentiate the disease from COVID-19.
  • |*COVID-19[MESH]
  • |*Respiratory Distress Syndrome/etiology[MESH]
  • |2019-nCoV Vaccine mRNA-1273[MESH]
  • |Aged, 80 and over[MESH]
  • |Autopsy[MESH]
  • |COVID-19 Vaccines/adverse effects[MESH]
  • |Dyspnea[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2[MESH]


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