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10.1039/d1ra06589k

http://scihub22266oqcxt.onion/10.1039/d1ra06589k
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35496844!9041347!35496844
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suck abstract from ncbi


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pmid35496844      RSC+Adv 2021 ; 11 (50): 31373-31376
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  • An efficient synthesis of RNA containing GS-441524: the nucleoside precursor of remdesivir #MMPMID35496844
  • Moorthy R; Kennelly SA; Rodriguez DJ; Harki DA
  • RSC Adv 2021[Sep]; 11 (50): 31373-31376 PMID35496844show ga
  • Remdesivir is an antiviral nucleoside phosphoramidate with activity against multiple viruses, including SARS-CoV-2. To enable studies of viral polymerases with RNA containing remdesivir, we report an efficient synthesis of a phosphoramidite of GS-441524, the nucleoside precursor of remdesivir, and its incorporation into RNA using automated solid-phase RNA synthesis.
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