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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Front+Mol+Biosci 2022 ; 9 (ä): 839809 Nephropedia Template TP
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Serum NMR Profiling Reveals Differential Alterations in the Lipoproteome Induced by Pfizer-BioNTech Vaccine in COVID-19 Recovered Subjects and Naive Subjects #MMPMID35480886
Ghini V; Maggi L; Mazzoni A; Spinicci M; Zammarchi L; Bartoloni A; Annunziato F; Turano P
Front Mol Biosci 2022[]; 9 (ä): 839809 PMID35480886show ga
(1)H NMR spectra of sera have been used to define the changes induced by vaccination with Pfizer-BioNTech vaccine (2 shots, 21 days apart) in 10 COVID-19-recovered subjects and 10 COVID-19-naive subjects at different time points, starting from before vaccination, then weekly until 7 days after second injection, and finally 1 month after the second dose. The data show that vaccination does not induce any significant variation in the metabolome, whereas it causes changes at the level of lipoproteins. The effects are different in the COVID-19-recovered subjects with respect to the naive subjects, suggesting that a previous infection reduces the vaccine modulation of the lipoproteome composition.