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10.3390/ijms23084181 http://scihub22266oqcxt.onion/10.3390/ijms23084181 35456998!9026976!35456998     free     free     free       Int+J+Mol+Sci 2022 ; 23 (8): ä Nephropedia Template TP {{tp|p=35456998|t=2022. COVID-19 and One-Carbon Metabolism |pdf=|usr=}}{{35456998}} gab.com Text COVID-19 and One-Carbon Metabolism JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=35456998 #FOAvip Dysregulation of one-carbon metabolism affects a wide range of biological processes and is associated with a number of diseases, including cardiovascular disease, dementia, neural tube defects, and cancer. Accumulating evidence suggests that one-carbon metabolism plays an important role in COVID-19. The symptoms of long COVID-19 are similar to those presented by subjects suffering from vitamin B(12) deficiency (pernicious anemia). The metabolism of a cell infected by the SARS-CoV-2 virus is reshaped to fulfill the need for massive viral RNA synthesis, which requires de novo purine biosynthesis involving folate and one-carbon metabolism. Many aspects of host sulfur amino acid metabolism, particularly glutathione metabolism underlying antioxidant defenses, are also taken over by the SARS-CoV-2 virus. The purpose of this review is to summarize recent findings related to one-carbon metabolism and sulfur metabolites in COVID-19 and discuss how they inform strategies to combat the disease. Twit Text FOAVip COVID-19 and One-Carbon Metabolism ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=35456998 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35456998 #FOAvip English Wikipedia <ref>{{Cite pmid|35456998}}</ref> COVID-19 and One-Carbon Metabolism #MMPMID35456998 Perla-Kajan J; Jakubowski H Int J Mol Sci 2022[Apr]; 23 (8): ä PMID35456998show ga Dysregulation of one-carbon metabolism affects a wide range of biological processes and is associated with a number of diseases, including cardiovascular disease, dementia, neural tube defects, and cancer. Accumulating evidence suggests that one-carbon metabolism plays an important role in COVID-19. The symptoms of long COVID-19 are similar to those presented by subjects suffering from vitamin B(12) deficiency (pernicious anemia). The metabolism of a cell infected by the SARS-CoV-2 virus is reshaped to fulfill the need for massive viral RNA synthesis, which requires de novo purine biosynthesis involving folate and one-carbon metabolism. Many aspects of host sulfur amino acid metabolism, particularly glutathione metabolism underlying antioxidant defenses, are also taken over by the SARS-CoV-2 virus. The purpose of this review is to summarize recent findings related to one-carbon metabolism and sulfur metabolites in COVID-19 and discuss how they inform strategies to combat the disease. |*COVID-19/complications[MESH] |Carbon/metabolism[MESH] |Folic Acid/metabolism[MESH] |Homocysteine[MESH] |Humans[MESH] |Methionine/metabolism[MESH] |Post-Acute COVID-19 Syndrome[MESH] |SARS-CoV-2[MESH]COVID-19 and One-Carbon Metabolism (epmc).pdf DeepDyve Pubget Overpricing