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Gut microbial signature and gut-lung axis: A possible role in the therapy of COVID-19 #MMPMID35411301
Mahmoodpoor A; Shamekh A; Sanaie S
Bioimpacts 2022[]; 12 (2): 175-177 PMID35411301show ga
The impact of gut as the origin of different disorders has led to the "gut-origin concept" of diseases. The gut microbiome regulates host defenses against viral infections, thus dysbiosis can play a major role in triggering the cascade of inflammation and causing immune imbalances in COVID-19 patients. It appears that gut microbial signature in COVID-19 patients can be used as a potential diagnostic, therapeutic, and even a prognostic marker. Personalized nutrition therapy can be used by profiling the gut microbiota of individual patients and specialized probiotics/synbiotics to modify gut dysbiosis. Hence, improving overall immune responses can be recommended in these patients.