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10.1128/mmbr.00026-21 http://scihub22266oqcxt.onion/10.1128/mmbr.00026-21 35343760!9199417!35343760     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Microbiol+Mol+Biol+Rev 2022 ; 86 (2): e0002621 Nephropedia Template TP {{tp|p=35343760|t=2022. Molecular Virology of SARS-CoV-2 and Related Coronaviruses |pdf=|usr=}}{{35343760}} gab.com Text Molecular Virology of SARS-CoV-2 and Related Coronaviruses JO: Microbiol Mol Biol Rev http://www.kidney.de/pget.php?&tw=1&pmid=35343760 #FOAvip Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The global COVID-19 pandemic continues to threaten the lives of hundreds of millions of people, with a severe negative impact on the global economy. Although several COVID-19 vaccines are currently being administered, none of them is 100% effective. Moreover, SARS-CoV-2 variants remain an important worldwide public health issue. Hence, the accelerated development of efficacious antiviral agents is urgently needed. Coronavirus depends on various host cell factors for replication. An ongoing research objective is the identification of host factors that could be exploited as targets for drugs and compounds effective against SARS-CoV-2. In the present review, we discuss the molecular mechanisms of SARS-CoV-2 and related coronaviruses, focusing on the host factors or pathways involved in SARS-CoV-2 replication that have been identified by genome-wide CRISPR screening. Twit Text FOAVip Molecular Virology of SARS-CoV-2 and Related Coronaviruses ????Microbiol Mol Biol Rev http://www.kidney.de/pget.php?&tw=1&pmid=35343760 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35343760 #FOAvip English Wikipedia <ref>{{Cite pmid|35343760}}</ref> Molecular Virology of SARS-CoV-2 and Related Coronaviruses #MMPMID35343760 Kung YA; Lee KM; Chiang HJ; Huang SY; Wu CJ; Shih SR Microbiol Mol Biol Rev 2022[Jun]; 86 (2): e0002621 PMID35343760show ga Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The global COVID-19 pandemic continues to threaten the lives of hundreds of millions of people, with a severe negative impact on the global economy. Although several COVID-19 vaccines are currently being administered, none of them is 100% effective. Moreover, SARS-CoV-2 variants remain an important worldwide public health issue. Hence, the accelerated development of efficacious antiviral agents is urgently needed. Coronavirus depends on various host cell factors for replication. An ongoing research objective is the identification of host factors that could be exploited as targets for drugs and compounds effective against SARS-CoV-2. In the present review, we discuss the molecular mechanisms of SARS-CoV-2 and related coronaviruses, focusing on the host factors or pathways involved in SARS-CoV-2 replication that have been identified by genome-wide CRISPR screening. |*COVID-19[MESH] |*SARS-CoV-2/genetics[MESH] |Antiviral Agents/pharmacology/therapeutic use[MESH] |COVID-19 Vaccines[MESH] |Humans[MESH]Molecular Virology of SARS-CoV-2 and Related Coronaviruses (epmc).pdf DeepDyve Pubget Overpricing