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10.1080/22221751.2022.2059400 http://scihub22266oqcxt.onion/10.1080/22221751.2022.2059400 35343389!9037197!35343389     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\35343389.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Emerg+Microbes+Infect 2022 ; 11 (1): 1115-1125 Nephropedia Template TP {{tp|p=35343389|t=2022. SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients |pdf=|usr=}}{{35343389}} gab.com Text SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients JO: Emerg Microbes Infect http://www.kidney.de/pget.php?&tw=1&pmid=35343389 #FOAvip Diabetes mellitus (DM) is one of the most common underlying diseases that may aggravates COVID-19. In the present study, we explored islet function, the presence of SARS-CoV-2 and pathological changes in the pancreas of patients with COVID-19. Oral glucose tolerance tests (OGTTs) and the C-peptide release test demonstrated a decrease in glucose-stimulated C-peptide secretory capacity and an increase in HbA1c levels in patients with COVID-19. The prediabetic conditions appeared to be more significant in the severe group than in the moderate group. SARS-CoV-2 receptors (ACE2, CD147, TMPRSS2 and neuropilin-1) were expressed in pancreatic tissue. In addition to SARS-CoV-2 virus spike protein and virus RNA, coronavirus-like particles were present in the autophagolysosomes of pancreatic acinar cells of a patient with COVID-19. Furthermore, the expression and distribution of various proteins in pancreatic islets of patients with COVID-19 were altered. These data suggest that SARS-CoV-2 in the pancreas may directly or indirectly impair islet function. Twit Text FOAVip SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients ????Emerg Microbes Infect http://www.kidney.de/pget.php?&tw=1&pmid=35343389 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35343389 #FOAvip English Wikipedia <ref>{{Cite pmid|35343389}}</ref> SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients #MMPMID35343389 Ji N; Zhang M; Ren L; Wang Y; Hu B; Xiang J; Gong Y; Wu C; Qu G; Ding W; Yin Z; Li S; Wang Z; Zhou L; Chen X; Ma Y; Tang J; Liu Y; Liu L; Huang M Emerg Microbes Infect 2022[Dec]; 11 (1): 1115-1125 PMID35343389show ga Diabetes mellitus (DM) is one of the most common underlying diseases that may aggravates COVID-19. In the present study, we explored islet function, the presence of SARS-CoV-2 and pathological changes in the pancreas of patients with COVID-19. Oral glucose tolerance tests (OGTTs) and the C-peptide release test demonstrated a decrease in glucose-stimulated C-peptide secretory capacity and an increase in HbA1c levels in patients with COVID-19. The prediabetic conditions appeared to be more significant in the severe group than in the moderate group. SARS-CoV-2 receptors (ACE2, CD147, TMPRSS2 and neuropilin-1) were expressed in pancreatic tissue. In addition to SARS-CoV-2 virus spike protein and virus RNA, coronavirus-like particles were present in the autophagolysosomes of pancreatic acinar cells of a patient with COVID-19. Furthermore, the expression and distribution of various proteins in pancreatic islets of patients with COVID-19 were altered. These data suggest that SARS-CoV-2 in the pancreas may directly or indirectly impair islet function. |*COVID-19[MESH] |*Diabetes Mellitus/metabolism[MESH] |C-Peptide/metabolism[MESH] |Humans[MESH] |Pancreas[MESH]SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19(epmc).pdf DeepDyve Pubget Overpricing