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10.1016/j.mvr.2022.104361 http://scihub22266oqcxt.onion/10.1016/j.mvr.2022.104361 35339493!8942583!35339493     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Microvasc+Res 2022 ; 142 (ä): 104361 Nephropedia Template TP {{tp|p=35339493|t=2022. Detailed videocapillaroscopic microvascular changes detectable in adult COVID-19 survivors |pdf=|usr=}}{{35339493}} gab.com Text Detailed videocapillaroscopic microvascular changes detectable in adult COVID-19 survivors JO: Microvasc Res http://www.kidney.de/pget.php?&tw=1&pmid=35339493 #FOAvip OBJECTIVE: COVID-19 is a multisystem disease that causes endothelial dysfunction and organ damage. Aim of the study was to evaluate the microvascular status in COVID-19 survivors with past different disease severity, in comparison with age and sex-matched primary Raynaud's phenomenon (PRP) patients and control subjects (CNT), including possible effects of concomitant therapies. METHODS: Sixty-one COVID-19 survivors (mean age 58 +/- 13 years, mean days from disease onset 126 +/- 53 and mean days from recovery 104 +/- 53), thirty-one PRP patients (mean age 59 +/- 15 years, mean disease duration 11 +/- 10 years) and thirty CNT (mean age 58 +/- 13 years) underwent nailfold videocapillaroscopy (NVC) examination. The following capillaroscopic parameters were searched and scored (0-3): dilated capillaries, giant capillaries, isolated microhemorrhages, capillary ramifications (angiogenesis) and capillary number, including absolute capillary number per linear millimeter at the nailfold bed. RESULTS: The mean nailfold capillary number per linear millimeter was significantly lower in COVID-19 survivors when compared with PRP patients and CNT (univariate and multivariate analysis p < 0.001). On the contrary, COVID-19 survivors showed significantly less isolated microhemorrhages than PRP patients and CNT (univariate and multivariate analysis, p = 0.005 and p = 0.012, respectively). No statistically significant difference was observed between COVID-19 survivors and control groups concerning the frequency of dilated capillaries and capillary ramifications. COVID-19 selective therapies showed a promising trend on preserving capillary loss and deserving further investigations. CONCLUSIONS: SARS-CoV-2 seems to mainly induce a significant loss of capillaries in COVID-19 survivors at detailed NVC analysis in comparison to controls. The presence of a significant reduced score for isolated microhaemorrhages in COVID-19 survivors deserves further analysis. Twit Text FOAVip Detailed videocapillaroscopic microvascular changes detectable in adult COVID-19 survivors ????Microvasc Res http://www.kidney.de/pget.php?&tw=1&pmid=35339493 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35339493 #FOAvip English Wikipedia <ref>{{Cite pmid|35339493}}</ref> Detailed videocapillaroscopic microvascular changes detectable in adult COVID-19 survivors #MMPMID35339493 Sulli A; Gotelli E; Bica PF; Schiavetti I; Pizzorni C; Aloe T; Grosso M; Barisione E; Paolino S; Smith V; Cutolo M Microvasc Res 2022[Jul]; 142 (ä): 104361 PMID35339493show ga OBJECTIVE: COVID-19 is a multisystem disease that causes endothelial dysfunction and organ damage. Aim of the study was to evaluate the microvascular status in COVID-19 survivors with past different disease severity, in comparison with age and sex-matched primary Raynaud's phenomenon (PRP) patients and control subjects (CNT), including possible effects of concomitant therapies. METHODS: Sixty-one COVID-19 survivors (mean age 58 +/- 13 years, mean days from disease onset 126 +/- 53 and mean days from recovery 104 +/- 53), thirty-one PRP patients (mean age 59 +/- 15 years, mean disease duration 11 +/- 10 years) and thirty CNT (mean age 58 +/- 13 years) underwent nailfold videocapillaroscopy (NVC) examination. The following capillaroscopic parameters were searched and scored (0-3): dilated capillaries, giant capillaries, isolated microhemorrhages, capillary ramifications (angiogenesis) and capillary number, including absolute capillary number per linear millimeter at the nailfold bed. RESULTS: The mean nailfold capillary number per linear millimeter was significantly lower in COVID-19 survivors when compared with PRP patients and CNT (univariate and multivariate analysis p < 0.001). On the contrary, COVID-19 survivors showed significantly less isolated microhemorrhages than PRP patients and CNT (univariate and multivariate analysis, p = 0.005 and p = 0.012, respectively). No statistically significant difference was observed between COVID-19 survivors and control groups concerning the frequency of dilated capillaries and capillary ramifications. COVID-19 selective therapies showed a promising trend on preserving capillary loss and deserving further investigations. CONCLUSIONS: SARS-CoV-2 seems to mainly induce a significant loss of capillaries in COVID-19 survivors at detailed NVC analysis in comparison to controls. The presence of a significant reduced score for isolated microhaemorrhages in COVID-19 survivors deserves further analysis. |*COVID-19/diagnosis[MESH] |*Nails/blood supply[MESH] |Adult[MESH] |Aged[MESH] |Capillaries[MESH] |Humans[MESH] |Microscopic Angioscopy[MESH] |Middle Aged[MESH] |SARS-CoV-2[MESH]Detailed videocapillaroscopic microvascular changes detectable in adul(epmc).pdf DeepDyve Pubget Overpricing