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10.3390/v14030565

http://scihub22266oqcxt.onion/10.3390/v14030565
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35336973!8949226!35336973
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suck abstract from ncbi


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pmid35336973      Viruses 2022 ; 14 (3): ä
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  • COVID-19 Vaccination Limits Systemic Danger Signals in SARS-CoV-2 Infected Patients #MMPMID35336973
  • Angioni R; Sasset L; Cioccarelli C; Sanchez-Rodriguez R; Bertoldi N; Putaggio CC; Viola A; Cattelan A; Molon B
  • Viruses 2022[Mar]; 14 (3): ä PMID35336973show ga
  • Vaccination with an mRNA COVID-19 vaccine determines not only a consistent reduction in the risk of SARS-CoV-2 infection but also contributes to disease attenuation in infected people. Of note, hyperinflammation and damage-associated molecular patterns (DAMPs) have been clearly associated with severe illness and poor prognosis in COVID-19 patients. In this report, we revealed a significant reduction in the levels of IL-1ss and DAMPs molecules, as S100A8 and High Mobility Group Protein B1 (HMGB1), in vaccinated patients as compared to non-vaccinated ones. COVID-19 vaccination indeed prevents severe clinical manifestations in patients and limits the release of systemic danger signals in SARS-CoV-2 infected people.
  • |*COVID-19/prevention & control[MESH]
  • |*Viral Vaccines[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2[MESH]


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