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10.1038/s41419-022-04674-3 http://scihub22266oqcxt.onion/10.1038/s41419-022-04674-3 35288537!8919172!35288537     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Death+Dis 2022 ; 13 (3): 235 Nephropedia Template TP {{tp|p=35288537|t=2022. Plasma proteomic and metabolomic characterization of COVID-19 survivors 6 months after discharge |pdf=|usr=}}{{35288537}} gab.com Text Plasma proteomic and metabolomic characterization of COVID-19 survivors 6 months after discharge JO: Cell Death Dis http://www.kidney.de/pget.php?&tw=1&pmid=35288537 #FOAvip Coronavirus disease 2019 (COVID-19) has gained prominence as a global pandemic. Studies have suggested that systemic alterations persist in a considerable proportion of COVID-19 patients after hospital discharge. We used proteomic and metabolomic approaches to analyze plasma samples obtained from 30 healthy subjects and 54 COVID-19 survivors 6 months after discharge from the hospital, including 30 non-severe and 24 severe patients. Through this analysis, we identified 1019 proteins and 1091 metabolites. The differentially expressed proteins and metabolites were then subjected to Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis. Among the patients evaluated, 41% of COVID-19 survivors reported at least one clinical symptom and 26.5% showed lung imaging abnormalities at 6 months after discharge. Plasma proteomics and metabolomics analysis showed that COVID-19 survivors differed from healthy control subjects in terms of the extracellular matrix, immune response, and hemostasis pathways. COVID-19 survivors also exhibited abnormal lipid metabolism, disordered immune response, and changes in pulmonary fibrosis-related proteins. COVID-19 survivors show persistent proteomic and metabolomic abnormalities 6 months after discharge from the hospital. Hence, the recovery period for COVID-19 survivors may be longer. Twit Text FOAVip Plasma proteomic and metabolomic characterization of COVID-19 survivors 6 months after discharge ????Cell Death Dis http://www.kidney.de/pget.php?&tw=1&pmid=35288537 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35288537 #FOAvip English Wikipedia <ref>{{Cite pmid|35288537}}</ref> Plasma proteomic and metabolomic characterization of COVID-19 survivors 6 months after discharge #MMPMID35288537 Li H; Li X; Wu Q; Wang X; Qin Z; Wang Y; He Y; Wu Q; Li L; Chen H Cell Death Dis 2022[Mar]; 13 (3): 235 PMID35288537show ga Coronavirus disease 2019 (COVID-19) has gained prominence as a global pandemic. Studies have suggested that systemic alterations persist in a considerable proportion of COVID-19 patients after hospital discharge. We used proteomic and metabolomic approaches to analyze plasma samples obtained from 30 healthy subjects and 54 COVID-19 survivors 6 months after discharge from the hospital, including 30 non-severe and 24 severe patients. Through this analysis, we identified 1019 proteins and 1091 metabolites. The differentially expressed proteins and metabolites were then subjected to Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis. Among the patients evaluated, 41% of COVID-19 survivors reported at least one clinical symptom and 26.5% showed lung imaging abnormalities at 6 months after discharge. Plasma proteomics and metabolomics analysis showed that COVID-19 survivors differed from healthy control subjects in terms of the extracellular matrix, immune response, and hemostasis pathways. COVID-19 survivors also exhibited abnormal lipid metabolism, disordered immune response, and changes in pulmonary fibrosis-related proteins. COVID-19 survivors show persistent proteomic and metabolomic abnormalities 6 months after discharge from the hospital. Hence, the recovery period for COVID-19 survivors may be longer. |COVID-19/*mortality[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Metabolomics/*methods[MESH] |Middle Aged[MESH] |Patient Discharge/*statistics & numerical data[MESH] |Proteomics/*methods[MESH] |Severe acute respiratory syndrome-related coronavirus/*pathogenicity[MESH] |Survivors[MESH]Plasma proteomic and metabolomic characterization of COVID-19 survivor(epmc).pdf DeepDyve Pubget Overpricing