Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1126/science.abi9591 http://scihub22266oqcxt.onion/10.1126/science.abi9591 35258337!8995031!35258337     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=35258337&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Science 2022 ; 376 (6590): eabi9591 Nephropedia Template TP {{tp|p=35258337|t=2022. KIR(+)CD8(+) T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 |pdf=|usr=}}{{35258337}} gab.com Text KIR(+)CD8(+) T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 JO: Science http://www.kidney.de/pget.php?&tw=1&pmid=35258337 #FOAvip In this work, we find that CD8(+) T cells expressing inhibitory killer cell immunoglobulin-like receptors (KIRs) are the human equivalent of Ly49(+)CD8(+) regulatory T cells in mice and are increased in the blood and inflamed tissues of patients with a variety of autoimmune diseases. Moreover, these CD8(+) T cells efficiently eliminated pathogenic gliadin-specific CD4(+) T cells from the leukocytes of celiac disease patients in vitro. We also find elevated levels of KIR(+)CD8(+) T cells, but not CD4(+) regulatory T cells, in COVID-19 patients, correlating with disease severity and vasculitis. Selective ablation of Ly49(+)CD8(+) T cells in virus-infected mice led to autoimmunity after infection. Our results indicate that in both species, these regulatory CD8(+) T cells act specifically to suppress pathogenic T cells in autoimmune and infectious diseases. Twit Text FOAVip KIR(+)CD8(+) T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 ????Science http://www.kidney.de/pget.php?&tw=1&pmid=35258337 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35258337 #FOAvip English Wikipedia <ref>{{Cite pmid|35258337}}</ref> KIR(+)CD8(+) T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 #MMPMID35258337 Li J; Zaslavsky M; Su Y; Guo J; Sikora MJ; van Unen V; Christophersen A; Chiou SH; Chen L; Li J; Ji X; Wilhelmy J; McSween AM; Palanski BA; Mallajosyula VVA; Bracey NA; Dhondalay GKR; Bhamidipati K; Pai J; Kipp LB; Dunn JE; Hauser SL; Oksenberg JR; Satpathy AT; Robinson WH; Dekker CL; Steinmetz LM; Khosla C; Utz PJ; Sollid LM; Chien YH; Heath JR; Fernandez-Becker NQ; Nadeau KC; Saligrama N; Davis MM Science 2022[Apr]; 376 (6590): eabi9591 PMID35258337show ga In this work, we find that CD8(+) T cells expressing inhibitory killer cell immunoglobulin-like receptors (KIRs) are the human equivalent of Ly49(+)CD8(+) regulatory T cells in mice and are increased in the blood and inflamed tissues of patients with a variety of autoimmune diseases. Moreover, these CD8(+) T cells efficiently eliminated pathogenic gliadin-specific CD4(+) T cells from the leukocytes of celiac disease patients in vitro. We also find elevated levels of KIR(+)CD8(+) T cells, but not CD4(+) regulatory T cells, in COVID-19 patients, correlating with disease severity and vasculitis. Selective ablation of Ly49(+)CD8(+) T cells in virus-infected mice led to autoimmunity after infection. Our results indicate that in both species, these regulatory CD8(+) T cells act specifically to suppress pathogenic T cells in autoimmune and infectious diseases. |*Autoimmune Diseases[MESH] |*COVID-19[MESH] |Animals[MESH] |CD8-Positive T-Lymphocytes[MESH] |Humans[MESH] |Mice[MESH] |Receptors, KIR[MESH]KIR(+)CD8(+) T cells suppress pathogenic T cells and are active in aut(epmc).pdf DeepDyve Pubget Overpricing