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10.3390/v14020322 http://scihub22266oqcxt.onion/10.3390/v14020322 35215915!8878378!35215915     free     free     free  :   free Nephropedia Template TP {{tp|p=35215915|t=2022. Secondary Structure of Subgenomic RNA M of SARS-CoV-2 |pdf=|usr=}} gab.com Text Secondary Structure of Subgenomic RNA M of SARS-CoV-2 JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=35215915 #FOAvip SARS-CoV-2 belongs to the Coronavirinae family. Like other coronaviruses, SARS-CoV-2 is enveloped and possesses a positive-sense, single-stranded RNA genome of ~30 kb. Genomic RNA is used as the template for replication and transcription. During these processes, positive-sense genomic RNA (gRNA) and subgenomic RNAs (sgRNAs) are created. Several studies presented the importance of the genomic RNA secondary structure in SARS-CoV-2 replication. However, the structure of sgRNAs has remained largely unsolved so far. In this study, we probed the sgRNA M model of SARS-CoV-2 in vitro. The presented model molecule includes 5'UTR and a coding sequence of gene M. This is the first experimentally informed secondary structure model of sgRNA M, which presents features likely to be important in sgRNA M function. The knowledge of sgRNA M structure provides insights to better understand virus biology and could be used for designing new therapeutics. Twit Text FOAVip Secondary Structure of Subgenomic RNA M of SARS-CoV-2 🦆🦆Viruses http://www.kidney.de/pget.php?&tw=1&pmid=35215915 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35215915 #FOAvip English Wikipedia <ref>{{Cite pmid|35215915}}</ref> Secondary Structure of Subgenomic RNA M of SARS-CoV-2 #MMPMID35215915 Soszynska-Jozwiak M; Ruszkowska A; Kierzek R; O'Leary CA; Moss WN; Kierzek E Viruses 2022[Feb]; 14 (2): ä PMID35215915show ga SARS-CoV-2 belongs to the Coronavirinae family. Like other coronaviruses, SARS-CoV-2 is enveloped and possesses a positive-sense, single-stranded RNA genome of ~30 kb. Genomic RNA is used as the template for replication and transcription. During these processes, positive-sense genomic RNA (gRNA) and subgenomic RNAs (sgRNAs) are created. Several studies presented the importance of the genomic RNA secondary structure in SARS-CoV-2 replication. However, the structure of sgRNAs has remained largely unsolved so far. In this study, we probed the sgRNA M model of SARS-CoV-2 in vitro. The presented model molecule includes 5'UTR and a coding sequence of gene M. This is the first experimentally informed secondary structure model of sgRNA M, which presents features likely to be important in sgRNA M function. The knowledge of sgRNA M structure provides insights to better understand virus biology and could be used for designing new therapeutics. |*Genome, Viral[MESH] |5' Untranslated Regions[MESH] |COVID-19/virology[MESH] |Genomics[MESH] |Humans[MESH] |Open Reading Frames[MESH] |RNA, Viral/*chemistry/genetics[MESH] |SARS-CoV-2/*genetics[MESH] |Transcription, Genetic[MESH]Secondary Structure of Subgenomic RNA M of SARS-CoV-2 (epmc).pdf DeepDyve Pubget Overpricing