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10.1134/S0026893322010022

http://scihub22266oqcxt.onion/10.1134/S0026893322010022
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35194246!8853348!35194246
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suck abstract from ncbi


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pmid35194246      Mol+Biol 2022 ; 56 (1): 72-89
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  • Genetic Engineering Systems to Study Human Viral Pathogens from the Coronaviridae Family #MMPMID35194246
  • Galkin SO; Anisenko AN; Shadrina OA; Gottikh MB
  • Mol Biol 2022[]; 56 (1): 72-89 PMID35194246show ga
  • The COVID-19 pandemic caused by the previously unknown SARS-CoV-2 Betacoronavirus made it extremely important to develop simple and safe cellular systems which allow manipulation of the viral genome and high-throughput screening of its potential inhibitors. In this review, we made an attempt at summarizing the currently existing data on genetic engineering systems used to study not only SARS-CoV-2, but also other viruses from the Coronaviridae family. In addition, the review covers the basic knowledge about the structure and the life cycle of coronaviruses.
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