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10.3390/jcm11030788 http://scihub22266oqcxt.onion/10.3390/jcm11030788 35160240!8836951!35160240     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Clin+Med 2022 ; 11 (3): ä Nephropedia Template TP {{tp|p=35160240|t=2022. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients |pdf=|usr=}}{{35160240}} gab.com Text Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients JO: J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=35160240 #FOAvip Critical COVID-19 is a life-threatening disease characterized by severe hypoxemia with complex pathophysiological mechanisms that are not yet completely understood. A pathological shift in the oxyhemoglobin curve (ODC) was previously described through the analysis of p50, intended as the oxygen tension at which hemoglobin is saturated by oxygen at 50%. The aim of this study was to analyze Hb-O(2) affinity features over time in a cohort of critically ill COVID-19 patients, through the analysis of ODC p50 behavior. A retrospective analysis was performed; through multiple arterial blood gas (ABG) analyses, each p50 was calculated and normalized according to PaCO(2), pH and temperature; patients' p50 evolution over time was reported, comparing the first 3 days (early p50s) with the last 3 days (late p50s) of ICU stay. A total of 3514 ABG analyses of 32 consecutive patients were analyzed. The majority of patients presented a left shift over time (p = 0.03). A difference between early p50s and late p50s was found (20.63 +/- 2.1 vs. 18.68 +/- 3.3 mmHg, p = 0.03); median p50 of deceased patients showed more right shifts than those of alive patients (24.1 vs. 18.45 mmHg, p = 0.01). One-way ANOVA revealed a p50 variance greater in the early p50s (sigma(2) = 8.6) than in the late p50s (sigma(2) = 3.84), associated with a reduction over time (p < 0.001). Comparing the Hb-O(2) affinity in critically ill COVID-19 patients between ICU admission and ICU discharge, a temporal shift in the ODC was observed. Twit Text FOAVip Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients ????J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=35160240 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35160240 #FOAvip English Wikipedia <ref>{{Cite pmid|35160240}}</ref> Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients #MMPMID35160240 Ceruti S; Minotti B; Glotta A; Biggiogero M; Bona G; Marzano M; Greco P; Spagnoletti M; Garzoni C; Bendjelid K J Clin Med 2022[Jan]; 11 (3): ä PMID35160240show ga Critical COVID-19 is a life-threatening disease characterized by severe hypoxemia with complex pathophysiological mechanisms that are not yet completely understood. A pathological shift in the oxyhemoglobin curve (ODC) was previously described through the analysis of p50, intended as the oxygen tension at which hemoglobin is saturated by oxygen at 50%. The aim of this study was to analyze Hb-O(2) affinity features over time in a cohort of critically ill COVID-19 patients, through the analysis of ODC p50 behavior. A retrospective analysis was performed; through multiple arterial blood gas (ABG) analyses, each p50 was calculated and normalized according to PaCO(2), pH and temperature; patients' p50 evolution over time was reported, comparing the first 3 days (early p50s) with the last 3 days (late p50s) of ICU stay. A total of 3514 ABG analyses of 32 consecutive patients were analyzed. The majority of patients presented a left shift over time (p = 0.03). A difference between early p50s and late p50s was found (20.63 +/- 2.1 vs. 18.68 +/- 3.3 mmHg, p = 0.03); median p50 of deceased patients showed more right shifts than those of alive patients (24.1 vs. 18.45 mmHg, p = 0.01). One-way ANOVA revealed a p50 variance greater in the early p50s (sigma(2) = 8.6) than in the late p50s (sigma(2) = 3.84), associated with a reduction over time (p < 0.001). Comparing the Hb-O(2) affinity in critically ill COVID-19 patients between ICU admission and ICU discharge, a temporal shift in the ODC was observed. äTemporal Changes in the Oxyhemoglobin Dissociation Curve of Critically(epmc).pdf DeepDyve Pubget Overpricing