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10.3389/fimmu.2021.769442 http://scihub22266oqcxt.onion/10.3389/fimmu.2021.769442 35154070!8828559!35154070     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2021 ; 12 (ä): 769442 Nephropedia Template TP {{tp|p=35154070|t=2021. T-Cell Repertoire Characteristics of Asymptomatic and Re-Detectable Positive COVID-19 Patients |pdf=|usr=}}{{35154070}} gab.com Text T-Cell Repertoire Characteristics of Asymptomatic and Re-Detectable Positive COVID-19 Patients JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=35154070 #FOAvip The prevention of the COVID-19 pandemic is highly complicated by the prevalence of asymptomatic and recurrent infection. Many previous immunological studies have focused on symptomatic and convalescent patients, while the immune responses in asymptomatic patients and re-detectable positive cases remain unclear. Here we comprehensively analyzed the peripheral T-cell receptor (TCR) repertoire of 54 COVID-19 patients in different courses, including asymptomatic, symptomatic, convalescent, and re-detectable positive cases. We identified a set of V-J gene combinations characterizing the upward immune responses through asymptomatic and symptomatic courses. Furthermore, some of these V-J combinations could be awakened in the re-detectable positive cases, which may help predict the risk of recurrent infection. Therefore, TCR repertoire examination has the potential to strengthen the clinical surveillance and the immunotherapy development for COVID-19. Twit Text FOAVip T-Cell Repertoire Characteristics of Asymptomatic and Re-Detectable Positive COVID-19 Patients ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=35154070 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35154070 #FOAvip English Wikipedia <ref>{{Cite pmid|35154070}}</ref> T-Cell Repertoire Characteristics of Asymptomatic and Re-Detectable Positive COVID-19 Patients #MMPMID35154070 Li Y; Hu J; Wang Y; Liu D; Shi Y; Zhang J; Liu Y; Lin D; Lin J; Hu W; He H; Wang W; Fan W; Li L; Wang D; Wang K; Xu J Front Immunol 2021[]; 12 (ä): 769442 PMID35154070show ga The prevention of the COVID-19 pandemic is highly complicated by the prevalence of asymptomatic and recurrent infection. Many previous immunological studies have focused on symptomatic and convalescent patients, while the immune responses in asymptomatic patients and re-detectable positive cases remain unclear. Here we comprehensively analyzed the peripheral T-cell receptor (TCR) repertoire of 54 COVID-19 patients in different courses, including asymptomatic, symptomatic, convalescent, and re-detectable positive cases. We identified a set of V-J gene combinations characterizing the upward immune responses through asymptomatic and symptomatic courses. Furthermore, some of these V-J combinations could be awakened in the re-detectable positive cases, which may help predict the risk of recurrent infection. Therefore, TCR repertoire examination has the potential to strengthen the clinical surveillance and the immunotherapy development for COVID-19. |Adaptive Immunity/genetics/immunology[MESH] |Adult[MESH] |Aged[MESH] |Asymptomatic Infections[MESH] |COVID-19/immunology/*pathology[MESH] |Female[MESH] |Gene Expression/genetics[MESH] |Histocompatibility Antigens Class I/genetics[MESH] |Humans[MESH] |Immunoglobulin J-Chains/*genetics[MESH] |Immunoglobulin Variable Region/*genetics[MESH] |Male[MESH] |Middle Aged[MESH] |Receptors, Antigen, T-Cell/*genetics/immunology[MESH] |SARS-CoV-2/*immunology[MESH] |Severity of Illness Index[MESH] |T-Lymphocytes/*immunology[MESH]T-Cell Repertoire Characteristics of Asymptomatic and Re-Detectable Po(epmc).pdf DeepDyve Pubget Overpricing