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10.1016/j.nut.2021.111585

http://scihub22266oqcxt.onion/10.1016/j.nut.2021.111585
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suck abstract from ncbi


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pmid35131599      Nutrition 2022 ; 96 (ä): 111585
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  • Association of gut-related metabolites with respiratory symptoms in COVID-19: A proof-of-concept study #MMPMID35131599
  • Israr MZ; Ibrahim W; Salzano A; Sarmad S; Wilde MJ; Cordell RL; Greening NJ; Brightling CE; Siddiqui S; Suzuki T
  • Nutrition 2022[Apr]; 96 (ä): 111585 PMID35131599show ga
  • Gut-related metabolites have been linked with respiratory disease. The crosstalk between the gut and lungs suggests that gut health may be compromised in COVID-19. The aims of the present study were to analyze a panel of gut-related metabolites (acetyl-L-carnitine, betaine, choline, L-carnitine, trimethylamine, and trimethylamine N-oxide) in patients with COVID-19, matched with healthy individuals and patients with non-COVID-19 respiratory symptoms. As results, metabolites from this panel were impaired in patients with COVID-19 and were associated with the symptoms of breathlessness and temperature, and it was possible to differentiate between COVID-19 and asthma. Preliminary results showed that lower levels of betaine appeared to be associated with poor outcomes in patients with COVID-19, suggesting betaine as a marker of gut microbiome health.
  • |*COVID-19/complications[MESH]
  • |*Gastrointestinal Microbiome[MESH]
  • |Betaine[MESH]
  • |Carnitine[MESH]
  • |Choline[MESH]
  • |Humans[MESH]


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