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10.1002/JLB.1MR1221-345R http://scihub22266oqcxt.onion/10.1002/JLB.1MR1221-345R 35040189!9015493!35040189     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Leukoc+Biol 2022 ; 111 (6): 1159-1173 Nephropedia Template TP {{tp|p=35040189|t=2022. Neutrophil subsets and their differential roles in viral respiratory diseases |pdf=|usr=}}{{35040189}} gab.com Text Neutrophil subsets and their differential roles in viral respiratory diseases JO: J Leukoc Biol http://www.kidney.de/pget.php?&tw=1&pmid=35040189 #FOAvip Neutrophils play significant roles in immune homeostasis and as neutralizers of microbial infections. Recent evidence further suggests heterogeneity of neutrophil developmental and activation states that exert specialized effector functions during inflammatory disease conditions. Neutrophils can play multiple roles during viral infections, secreting inflammatory mediators and cytokines that contribute significantly to host defense and pathogenicity. However, their roles in viral immunity are not well understood. In this review, we present an overview of neutrophil heterogeneity and its impact on the course and severity of viral respiratory infectious diseases. We focus on the evidence demonstrating the crucial roles neutrophils play in the immune response toward respiratory infections, using influenza as a model. We further extend the understanding of neutrophil function with the studies pertaining to COVID-19 disease and its neutrophil-associated pathologies. Finally, we discuss the relevance of these results for future therapeutic options through targeting and regulating neutrophil-specific responses. Twit Text FOAVip Neutrophil subsets and their differential roles in viral respiratory diseases ????J Leukoc Biol http://www.kidney.de/pget.php?&tw=1&pmid=35040189 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35040189 #FOAvip English Wikipedia <ref>{{Cite pmid|35040189}}</ref> Neutrophil subsets and their differential roles in viral respiratory diseases #MMPMID35040189 Zhang Y; Wang Q; Mackay CR; Ng LG; Kwok I J Leukoc Biol 2022[Jun]; 111 (6): 1159-1173 PMID35040189show ga Neutrophils play significant roles in immune homeostasis and as neutralizers of microbial infections. Recent evidence further suggests heterogeneity of neutrophil developmental and activation states that exert specialized effector functions during inflammatory disease conditions. Neutrophils can play multiple roles during viral infections, secreting inflammatory mediators and cytokines that contribute significantly to host defense and pathogenicity. However, their roles in viral immunity are not well understood. In this review, we present an overview of neutrophil heterogeneity and its impact on the course and severity of viral respiratory infectious diseases. We focus on the evidence demonstrating the crucial roles neutrophils play in the immune response toward respiratory infections, using influenza as a model. We further extend the understanding of neutrophil function with the studies pertaining to COVID-19 disease and its neutrophil-associated pathologies. Finally, we discuss the relevance of these results for future therapeutic options through targeting and regulating neutrophil-specific responses. |*COVID-19[MESH] |*Virus Diseases/pathology[MESH] |Cytokines[MESH] |Humans[MESH] |Inflammation Mediators[MESH] |Neutrophil Activation[MESH]Neutrophil subsets and their differential roles in viral respiratory d(epmc).pdf DeepDyve Pubget Overpricing