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10.1177/03009858211067467

http://scihub22266oqcxt.onion/10.1177/03009858211067467
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35038930!9207983!35038930
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suck abstract from ncbi


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pmid35038930      Vet+Pathol 2022 ; 59 (4): 707-711
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  • Investigation of SARS-CoV-2 infection and associated lesions in exotic and companion animals #MMPMID35038930
  • Rotstein DS; Peloquin S; Proia K; Hart E; Lee J; Vyhnal KK; Sasaki E; Balamayooran G; Asin J; Southard T; Rothfeldt L; Venkat H; Mundschenk P; McDermott D; Crossley B; Ferro P; Gomez G; Henderson EH; Narayan P; Paulsen DB; Rekant S; Schroeder ME; Tell RM; Torchetti MK; Uzal FA; Carpenter A; Ghai R
  • Vet Pathol 2022[Jul]; 59 (4): 707-711 PMID35038930show ga
  • Documented natural infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in exotic and companion animals following human exposures are uncommon. Those documented in animals are typically mild and self-limiting, and infected animals have only infrequently died or been euthanized. Through a coordinated One Health initiative, necropsies were conducted on 5 animals from different premises that were exposed to humans with laboratory-confirmed SARS-CoV-2 infection. The combination of epidemiologic evidence of exposure and confirmatory real-time reverse transcriptase-polymerase chain reaction testing confirmed infection in 3 cats and a tiger. A dog was a suspect case based on epidemiologic evidence of exposure but tested negative for SARS-CoV-2. Four animals had respiratory clinical signs that developed 2 to 12 days after exposure. The dog had bronchointerstitial pneumonia and the tiger had bronchopneumonia; both had syncytial-like cells with no detection of SARS-CoV-2. Individual findings in the 3 cats included metastatic mammary carcinoma, congenital renal disease, and myocardial disease. Based on the necropsy findings and a standardized algorithm, SARS-CoV-2 infection was not considered the cause of death in any of the cases. Continued surveillance and necropsy examination of animals with fatal outcomes will further our understanding of natural SARS-CoV-2 infection in animals and the potential role of the virus in development of lesions.
  • |*COVID-19/veterinary[MESH]
  • |*Dog Diseases/diagnosis[MESH]
  • |*One Health[MESH]
  • |Animals[MESH]
  • |Dogs[MESH]
  • |Pets[MESH]


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