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10.3390/idr13040096

http://scihub22266oqcxt.onion/10.3390/idr13040096
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34940406!8700782!34940406
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suck abstract from ncbi


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pmid34940406      Infect+Dis+Rep 2021 ; 13 (4): 1053-1060
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  • Neck Circumference Predicts Mortality in Hospitalized COVID-19 Patients #MMPMID34940406
  • Di Bella S; Zerbato V; Sanson G; Roman-Pognuz E; De Cristofaro P; Palermo A; Valentini M; Gobbo Y; Jaracz AW; Bozic Hrzica E; Bresani-Salvi CC; Galindo AB; Crovella S; Luzzati R
  • Infect Dis Rep 2021[Dec]; 13 (4): 1053-1060 PMID34940406show ga
  • We aimed to determine whether neck circumference predicts mortality among hospitalized COVID-19 patients with respiratory failure. We performed a prospective multicenter (Italy and Brasil) study carried out from March to December 2020 on 440 hospitalized COVID-19 patients with respiratory failure. Baseline neck circumference was measured. The study outcome was 30- and 60-days mortality. Female and male participants were classified as "large neck" when exceeding fourth-quartile. Patients had a median age of 65 years (IQR 54-76), 68% were male. One-quarter of patients presented with grade-1 or higher obesity. The median neck circumference was 40 cm (IQR 38-43): 38 cm (IQR 36-40) for female and 41 cm (IQR 39-44) for male subjects. "Large neck" patients had a significantly higher prevalence of hypertension (63 vs. 48%), diabetes (33 vs. 19%), obesity (26 vs. 14%), and elevated C-reactive protein (CRP) (98 vs. 88%). The cumulative mortality rate was 13.1% (n = 52) and 15.9% (n = 63) at 30 and 60 days, respectively. After adjusting for age, BMI, relevant comorbidities, and high C-reactive protein to albumin ratio, "large neck" patients showed a significantly increased risk of death at 30- (adjusted HR 2.50; 95% CI 1.18-5.29; p = 0.017) and 60-days (adjusted HR 2.26; 95% CI 1.14-4.46; p = 0.019). Neck circumference is easy to collect and provides additional prognostic information to BMI. Among hospitalized COVID-19 patients with respiratory failure, those with large neck phenotype had a more than double risk of death at 30 and 60 days.
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