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10.1093/cid/ciab1040

http://scihub22266oqcxt.onion/10.1093/cid/ciab1040
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34932817!8903328!34932817
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suck abstract from ncbi

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  • Predictors of SARS-CoV-2 infection following high-risk exposure #MMPMID34932817
  • Andrejko KL; Pry J; Myers JF; Openshaw J; Watt J; Birkett N; DeGuzman JL; Barbaduomo CM; Dong ZN; Fang AT; Frost PM; Ho T; Javadi MH; Li SS; Tran VH; Wan C; Jain S; Lewnard JA
  • Clin Infect Dis 2021[Dec]; ä (ä): ä PMID34932817show ga
  • BACKGROUND: Non-pharmaceutical interventions (NPIs) are recommended for COVID-19 prevention. However, the effectiveness of NPIs in preventing SARS-CoV-2 transmission remains poorly quantified. METHODS: We conducted a test-negative design case-control study enrolling cases (testing positive for SARS-CoV-2) and controls (testing negative) with molecular SARS-CoV-2 diagnostic test results reported to California Department of Public Health between 24 February-12 November, 2021. We used conditional logistic regression to estimate adjusted odds ratios (aORs) of case status among participants who reported contact with an individual known or suspected to have been infected with SARS-CoV-2 ("high-risk exposure") /=3 hours (vs. shorter durations) among unvaccinated and partially-vaccinated individuals; excess risk associated with such exposures was mitigated among fully-vaccinated individuals. Cases were less likely than controls to report mask usage during high-risk exposures (aOR=0.50 [0.29-0.85]). The adjusted odds of case status was lower for fully-vaccinated (aOR=0.25 [0.15-0.43]) participants compared to unvaccinated participants. Benefits of mask usage were greatest among unvaccinated and partially-vaccinated participants, and in interactions involving non-household contacts or interactions occurring without physical contact. CONCLUSIONS: NPIs reduced the likelihood of SARS-CoV-2 infection following high-risk exposure. Vaccine effectiveness was substantial for partially and fully vaccinated persons.
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  • suck abstract from ncbi

    ä ä.ä 2021