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10.1186/s43044-021-00234-w

http://scihub22266oqcxt.onion/10.1186/s43044-021-00234-w
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suck abstract from ncbi


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pmid34928467      Egypt+Heart+J 2021 ; 73 (1): 108
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  • Bilirubin levels as an independent predictor of myocarditis in patients with COVID-19 #MMPMID34928467
  • Cosgun MS
  • Egypt Heart J 2021[Dec]; 73 (1): 108 PMID34928467show ga
  • BACKGROUND: Myocardial damage worsens the clinical course and prognosis of coronavirus disease 2019 (COVID-19) patients. High total bilirubin levels have been associated with a poor prognosis in COVID-19. This study aimed to investigate the predictive value of the total bilirubin level, a marker of heme oxygenase-1 enzyme activity, in determining myocarditis in patients with COVID-19. RESULTS: A total of 190 patients diagnosed with COVID-19 were enrolled in the study. The patients were divided into two groups based on their troponin positivity. The study group (n = 95) consisted of patients with high troponin, and the control group (n = 95) consisted of patients without high troponin levels. The D-dimer (727 [572-995] vs. 591 [440-790], p = 0.001), C-reactive protein (CRP) (30.0 [10-48] vs. 10.3 [5.8-15.9], p < 0.001), and total bilirubin (9.5 [8.2-12.1] vs. 7.0 [5.3-8.0], p < 0.001) levels were significantly higher in the study group. In multivariate analysis, CRP (odds ratio [OR]: 1.103; 95% confidence interval [CI]: 1.060-1.148; p < 0.001) and total bilirubin (OR: 1.612; 95% CI: 1.330-1.954; p < 0.001) levels were independent predictors of myocarditis in COVID-19. CONCLUSIONS: Total bilirubin levels can be used as an early predictor of myocarditis in COVID-19 and can contribute to therapy management.
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