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10.1016/j.sjbs.2021.11.061 http://scihub22266oqcxt.onion/10.1016/j.sjbs.2021.11.061 34924800!8666385!34924800     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Saudi+J+Biol+Sci 2022 ; 29 (4): 1947-1956 Nephropedia Template TP {{tp|p=34924800|t=2022. Therapeutic potential of induced iron depletion using iron chelators in Covid-19 |pdf=|usr=}}{{34924800}} gab.com Text Therapeutic potential of induced iron depletion using iron chelators in Covid-19 JO: Saudi J Biol Sci http://www.kidney.de/pget.php?&tw=1&pmid=34924800 #FOAvip Ferritin, which includes twenty-four light and heavy chains in varying proportions in different tissues, is primarily responsible for maintaining the body's iron metabolism. Its normal value is between 10 and 200 ngmL(-1) in men and between 30 and 300 ngmL(-1) in women. Iron is delivered to the tissue via them, and they act as immunomodulators, signaling molecules, and inflammatory markers. When ferritin level exceeds 1000 microgL(-1), the patient is categorized as having hyperferritinemia. Iron chelators such as deferiprone, deferirox, and deferoxamine are currently FDA approved to treat iron overload. The inflammation cascade and poor prognosis of COVID-19 may be attributed to high ferritin levels. Critically ill patients can benefit from deferasirox, an iron chelator administered orally at 20-40 mgkg(-1) once daily, as well as intravenous deferoxamine at 1000 mg initially followed by 500 mg every 4 to 12 h. It can be combined with monoclonal antibodies, antioxidants, corticosteroids, and lactoferrin to make iron chelation therapy effective for COVID-19 victims. In this article, we analyze the antiviral and antifibrotic activity of iron chelators, thereby promoting iron depletion therapy as a potentially innovative treatment strategy for COVID-19. Twit Text FOAVip Therapeutic potential of induced iron depletion using iron chelators in Covid-19 ????Saudi J Biol Sci http://www.kidney.de/pget.php?&tw=1&pmid=34924800 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34924800 #FOAvip English Wikipedia <ref>{{Cite pmid|34924800}}</ref> Therapeutic potential of induced iron depletion using iron chelators in Covid-19 #MMPMID34924800 Poonkuzhi Naseef P; Elayadeth-Meethal M; Mohammed Salim KT; Anjana A; Muhas C; Abdul Vajid K; Saheer Kuruniyan M Saudi J Biol Sci 2022[Apr]; 29 (4): 1947-1956 PMID34924800show ga Ferritin, which includes twenty-four light and heavy chains in varying proportions in different tissues, is primarily responsible for maintaining the body's iron metabolism. Its normal value is between 10 and 200 ngmL(-1) in men and between 30 and 300 ngmL(-1) in women. Iron is delivered to the tissue via them, and they act as immunomodulators, signaling molecules, and inflammatory markers. When ferritin level exceeds 1000 microgL(-1), the patient is categorized as having hyperferritinemia. Iron chelators such as deferiprone, deferirox, and deferoxamine are currently FDA approved to treat iron overload. The inflammation cascade and poor prognosis of COVID-19 may be attributed to high ferritin levels. Critically ill patients can benefit from deferasirox, an iron chelator administered orally at 20-40 mgkg(-1) once daily, as well as intravenous deferoxamine at 1000 mg initially followed by 500 mg every 4 to 12 h. It can be combined with monoclonal antibodies, antioxidants, corticosteroids, and lactoferrin to make iron chelation therapy effective for COVID-19 victims. In this article, we analyze the antiviral and antifibrotic activity of iron chelators, thereby promoting iron depletion therapy as a potentially innovative treatment strategy for COVID-19. äTherapeutic potential of induced iron depletion using iron chelators i(epmc).pdf DeepDyve Pubget Overpricing